The notorious amyloid precursor protein [1], central to Alzheimer’s disease pathogenesis, sports a new look on Alzforum’s Mutations database [2]. We added functional domains to the APP diagram, and now offer a separate depiction of the amyloid-β peptide and its multiple species. Enjoy the viewing, and explore our data set’s 60 variants with details on their clinical phenotypes, neuropathology, and molecular effects.