Catch-up – 11th Aging Research and Drug Discovery Meeting

Yuliia Haluza, Center for Regenerative Therapies Dresden, Germany, presents at the 11th Aging Research and Drug Discovery meeting: Axoloti epigenetic clock offers insights into the nature of negligible senescence

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Natalia Mitin, Sapere Bio, USA, presents at the 11th Aging Research and Drug Discovery meeting: Cellular senescence solutions: pioneering advances in clinical practice

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Morten Scheibye-Knudsen, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: Data driven interventions in human aging

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Steve Horvath, Altos Labs, USA, presents at the 11th Aging Research and Drug Discovery meeting: DNA methylation studies of maximum lifespan in mammals

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Vadim Gladyshev, Harvard Medical School, USA, presents at the 11th Aging Research and Drug Discovery meeting: Organ aging and rejuvenation

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Session presenters:
Lisa Melton, Nature Biotechnology
Garri Zmudze, LongeVC, Switzerland
Lars Hartenstein, McKinsey Health Institute, USA
Michael Baran, Pfizer, Inc., USA
Petr Sramek, Healthy Longevity Clinic, USA
Marie Kveiborg, Novo Nordisk Foundation, Denmark
Alex Zhavoronkov, Insilico Medicine, USA

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Joseph Takahashi, University of Texas Southwestern Medical Center, USA, presents at the 11th Aging Research and Drug Discovery meeting: Circadian Clock Regulation of Aging and Longevity

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Eric Verdin, Buck Institute, USA, presents at the 11th Aging Research and Drug Discovery meeting: Defining and measuring human immune aging

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Maximilian Unfried, National University of Singapore, Singapore, presents at the 11th Aging Research and Drug Discovery meeting: Lipid Aging Clocks as predictive and prognostic biomarker in cancer and inflammaging

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Luka Culig, National Institute on Aging (NIA), USA, presents at the 11th Aging Research and Drug Discovery meeting: Early-onset partial reprogramming slows down certain age-associated changes in the hematological, immune, and cognitive compartments of NOLIFE non-progeric mice

Andrew Adams, Eli Lilly & Company, USA, presents at the 11th Aging Research and Drug Discovery meeting: Can genetic medicine give us a world without disease

Frank Pun and Fedor Galkin, Insilico Medicine, Hong Kong and Abu Dhabi respectively, presents at the 11th Aging Research and Drug Discovery meeting: Dual-Purpose Target Discovery and Aging Research with PreciousGPT Models

Download P3GPT from Hugging Face : https://doi.org/10.57967/hf/2699

BioRxiv preprint: https://doi.org/10.1101/2024.07.25.60... ("Precious3GPT: Multimodal Multi-Species Multi-Omics Multi-Tissue Transformer for Aging Research and Drug Discovery")

Michael Petr from Tracked Biotechnologies, presents at the 11th Aging Research and Drug Discovery Meeting.

Lou Hawthorne, NaNotics, USA, presents at the 11th Aging Research and Drug Discovery meeting: NaNots: A Novel Platform for Adsorbing Soluble Drivers of Diseases & Aging

Vittorio Sebastiano, Turn Biotechnologies, USA, presents at the 11th Aging Research and Drug Discovery meeting.

David Furman, Stanford School of Medicine, USA, presents at the 11th Aging Research and Drug Discovery meeting: Microgravity Induced Artificial Organ Aging to Identify Geroprotective Drugs

Isabel Beerman, National Institute on Aging, USA, presents at the 11th Aging Research and Drug Discovery meeting: Effects of cyclic period feeding restriction in non-human primates

Aubrey de Grey, LEV Foundation, USA, presents at the 11th Aging Research and Drug Discovery meeting: Taking rejuvenation to longevity escape velocity: combinatorial rejuvenation in mice

Chris Rinsch, Timeline, the Switzerland, presents at the 11th Aging Research and Drug Discovery meeting: The Impact of the Postbiotic Urolithin A (Mitopure) on Health and Longevity

Nicholas Schork, Translational Genomics Research Institute, USA, presents at the 11th Aging Research and Drug Discovery meeting: Pentadecanoic Acid (C15:0) As a Geroprotector: Evolution, Aging Hallmarks, and a Preponderance of Evidence

Anissa Anindya Widjaja, Duke-NUS Medical School, Singapore, presents at the 11th Aging Research and Drug Discovery meeting: Inhibition of IL11 signalling extends mammalian healthspan and lifespan

Robin Mansukhani, Deciduous Therapeutics, USA, presents at the 11th Aging Research and Drug Discovery meeting: Restoring Immune Function to Ablate Senescent Cells and Treat Diseases of Aging

David A. Sinclair, Harvard Medical School, USA, presents at the 11th Aging Research and Drug Discovery meeting: The Information Theory of Aging: where do we stand?

Mara Fornaro, Novartis, Switzerland, presents at the 11th Aging Research and Drug Discovery meeting: Diseases of Aging and Regenerative medicine (DARe) in Novartis: elucidating how age-associated changes intersect with disease to support therapeutic discovery

Mourad Topors, Repair Biotechnologies, USA, presents at the 11th Aging Research and Drug Discovery meeting: Clearance of Excess Intracellular Free Cholesterol Reverses Cardiovascular and Metabolic Disease

Andreas Beyer, University of Cologne, Germany, presents at the 11th Aging Research and Drug Discovery meeting: Age-associated loss of gene expression control

Yuta Lee, Accelerated Biosciences, USA, presents at the 11th Aging Research and Drug Discovery meeting: Trophoblast Stem Cell Secretome for Cell Senescence

Anu Suomalainen, University of Helsinki, Finland, presents at the 11th Aging Research and Drug Discovery meeting: NAD and glutathione dynamics in human aging, disease and after NAD-booster treatment

Matias Fuentealba Valenzuela, University College London (UCL), UK, presents at the 11th Aging Research and Drug Discovery meeting: Harnessing epigenetics to estimate Intrinsic Capacity

Domenico DiFraia, Vera Gorbunova's laboratory in Rochester, USA, presents at the 11th Aging Research and Drug Discovery meeting: Ribosome machinery is a convergent target in the evolution of mammalian longevity

Yousin Suh, Columbia University, USA, presents at the 11th Aging Research and Drug Discovery meeting: In vitro heterochronic parabiosis identifies a multi-tissue geroprotective factor from young blood

Raghav Sehgal, Healthy Longevity clinic, USA, presents at the 11th Aging Research and Drug Discovery meeting: Translating Geroscience to Clinic

John Sedivy, Brown University, USA, presents at the 11th Aging Research and Drug Discovery meeting: Treatment of neurodegenerative disorders with reverse transcriptase inhibitors

Alexander Dakhovnik from Sydra, presents at the 11th Aging Research and Drug Discovery meeting.

Irina Moreira from PURRAI, presents at the 11th Aging Research and Drug Discovery meeting.

Garik Mkrtchyan from Vanaheim Bio, presents at the 11th Aging Research and Drug Discovery meeting.

Ivan Silio from ReVamp Bio, presents at the 11th Aging Research and Drug Discovery meeting.

Rafael Bottos from Aptah Bioscience, presents at the 11th Aging Research and Drug Discovery meeting.

Nika Pintar from Ani Biome, presents at the 11th Aging Research and Drug Discovery meeting.

Kennedy Schaal from Rejuve.Bio, presents at the 11th Aging Research and Drug Discovery meeting.

Jan Mousing from Mmimetika, presents at the 11th Aging Research and Drug Discovery meeting.

Nika Pintar, Ani Biome, Croatia, presents at the 11th Aging Research and Drug Discovery meeting: Microbiome modulation as AI algorithm

Evelyne Bischof, Renji Hospital, Shanghai and Sheba Longevity Center, presents at the 11th Aging Research and Drug Discovery meeting: Reciprocal Paths to Healthy Longevity for All : Integrating AI, Metaverse, and Interdisciplinary Clinical Practice for Both the Healthy and the Sick

Risa Starr, Longevity Biotechnology Association, USA, presents at the 11th Aging Research and Drug Discovery meeting: The Longevity Biotechnology Association: Helping Longevity Biotech thrive and prosper

Rozalyn Anderson, University of Wisconsin Madison, USA, presents at the 11th Aging Research and Drug Discovery meeting: Delayed Aging by Caloric Restriction

Boris Djordjevic, 199 Biotechnologies, UK, presents at the 11th Aging Research and Drug Discovery meeting: Translating to clinics

Nicholas Edward Stroustrup, Center for Genomic Regulation, Spain, presents at the 11th Aging Research and Drug Discovery meeting: Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony

Brian Kennedy, National University of Singapore, Singapore, presents at the 11th Aging Research and Drug Discovery meeting: Where are we in the Longevity Quest

Linda Partridge, University College London, UK, presents at the 11th Aging Research and Drug Discovery meeting: Geroprotection from combination drug treatments

Session Presenters:
Bruno Balen, Ani Biome, Croatia

Christine Huang, Hong Kong Quantum AI Lab and the University of Hong Kong

Anita D. Cosgrove, BS MA JD Precision Health Consultant

Xingli Wang, Fosun Pharma, China

Alireza Haghighi, Harvard Medical School, USA

Evelyne Bischof, Renji Hospital, Shanghai and Sheba Longevity Center, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Healthy Longevity Medicine as Discipline - Practice Guideline and Education for Healthcare Professionals in Academic Medicine

David W. Dodick, Mayo Clinic, USA, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Brain health and longevity

Jaron Rabinovici, Sheba Medical Center, Israel, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: HRT when and why?

Wei-Wu He, Human Longevity, USA, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Human Longevity - the Longitudinal Cohort of 10+ years for 100+ years

David Luu, LongevityDocs, USA, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: LongevityDocs

Andrew Steele, Scientist and writer, Germany, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Longevity science , medicine and advocacy

Andrew Steel: @DrAndrewSteele

Nicole Sirotin, Institute for Healthier Living Abu Dhabi, UAE, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Precision and Lifestyle - approach for healthy longevity

IHLAD: https://www.youtube.com/@IHL-AD

Sara Bonnes, Mayo Clinic, USA, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Healthy Longevity Clinics in Academic Medicine - the Mayo Clinic Experience

Tzipi Strauss, Chaim Sheba Medical Center, Tel Hashomer, Israel, presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Sheba Experience as First Longevity Department in an University Hospital

Andrea B. Maier, National University of Singapore, Singapore, USA presents at the 11th Aging Research and Drug Discovery meeting-Longevity Medicine Track: Healthy Longevity Clinical Research- the NUS Experience

Vakil Takhaveev, ETH Zurich, Switzerland, presents at the 11th Aging Research and Drug Discovery meeting: Sequencing oxidized guanines, abasic sites, and DNA breaks in the human genome: towards mechanistic biomarkers of aging

Zhiquan Li, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species

Zoe Du, Buck institute, USA, presents at the 11th Aging Research and Drug Discovery meeting: Tension and Gravity: The Forces at Play in Aging

Max Shokhirev, Tally Health, USA, presents at the 11th Aging Research and Drug Discovery meeting: Developing a next-generation buccal clock that associates with lifestyle and mortality

Jing-Dong Jackie Han, Peking-Tsinghua Center for Life Sciences, China, presents at the 11th Aging Research and Drug Discovery meeting: Measuring Aging with AI

Adam Antebi, Max Planck Institute, Germany, presents at the 11th Aging Research and Drug Discovery meeting: Insights into stem cell longevity, rejuvenation and senescence from diapause

Sara Hägg, Karolinska Institutet, Sweden, presents at the 11th Aging Research and Drug Discovery meeting: Drug repurposing for Alzheimer's disease using triangulation of evidence

Session Presenters:
Dr. Jamie Justice, Executive Director, XPRIZE Healthspan and EVP Health Domain

Dr. Steve Austad, Endowed Chair in Healthy Aging and Distinguished Professor of Biology, University of Alabama Birmingham

Dr. Nir Barzilai, Director, Institute for Aging Research at the Albert Einstein College of Medicine; Director, Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health’s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging

Dr. Thomas Rando, Director, UCLA Broad Stem Cell Research Center; Professor of Neurology, Stanford Medicine

Dr. Mehmood Khan, CEO of Hevolution Foundation, Saudi Arabia

Jan Vijg, Albert Einstein College of Medicine, USA, presents at the 11th Aging Research and Drug Discovery meeting: Functional impact of somatic mutations in aging: role of negative selection

Björn Schumacher, University of Cologne, Germany, presents at the 11th Aging Research and Drug Discovery meeting: Genome Stability in Aging: Mechanisms and Targets

Session Presenter: Dr. Brianna Stubbs, Director of Translational Science, Buck Institute for Research on Aging

Session Presenter: Dr. Lauren Pierpoint, Technical Lead, XPRIZE Healthspan

Uri Alon, Weizmann Institute of Science, Israel, facilitates the interactive session with the audience during the Physics in Aging Workshop.

Uri Alon, Weizmann Institute of Science, Israel, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: The saturating removal model of aging and age related-disease

Uri Alon, Weizmann Institute of Science, Israel, facilitates the interactive session with the audience during the Physics in Aging Workshop.

Joshua Johnson, University of Colorado Denver (AMC), presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: How Ovarian Aging Can Modify Chronological Aging

Mogens Høgh Jensen, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: Condensate Formation and DNA repair in Cell Signaling

Albert-László Barabási, Northeastern University, USA, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: Network Medicine of Aging

Nicholas Edward Stroustrup, Centre for Genomic Regulation, Barcelona Spain, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: The temporal scaling of C. elegans aging

Andrew Rutenberg, Dalhousie University, Canada, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: The Dynamics of Aging Health

Omer Karin, Imperial College London, UK, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: The physics of cell division, removal, differentiation, and reprogramming

Jan Gruber, University of Singapore, Singapore, presents at the 11th Aging Research and Drug Discovery meeting - Physics in Aging Workshop: Navigating feature space using death-clocks to maximise healthspan?

Session Presenters:
Dr. Laura Goetz, Medical Deputy, XPRIZE Healthspan
Dr. Alexander (Zan) Flemming, Founder and Executive Chairman, Kinexum
Dr. Bart van der Schueren, Associate Professor in Endocrinology, University of Leuven
Dr. Alberto Aparicio, Assistant Professor of Bioethics and Health Humanities, The University of Texas Medical Branch

Session Presenter: Dr. George Kuchel, Professor of Medicine, Travelers Chair in Geriatrics and Gerontology, and Director of the UConn Center on Aging, University of Connecticut

Session Presenter: Dr. Perminder Sachdev, Scientia Professor of Neuropsychiatry at UNSW Sydney, Co-Director of the Centre for Healthy Brain Ageing (CHeBA), and Clinical Director of the Neuropsychiatric Institute at Prince of Wales Hospital

Session Presenter: Dr. Steven Cummings, Scientific Director, California Pacific Medical Center Research Institute and University of California San Francisco (UCSF)

Session presenter: Dr. Eva Chin, Director, SOLVE FSHD

Session presenter: Nicholas Schork, Director, Translational Genomics Research Institute

Welcome and Introductions:
Dr. Jamie Justice, Executive Director, XPRIZE Healthspan and EVP Health Domain, USA and Dr. Mehmood Khan, CEO of Hevolution Foundation, Saudi Arabia

Virtual welcome messages by:
Dr. Peter H. Diamandis, XPRIZE Founder and Chairman of the Board, Dr. Mehmood Khan, CEO of Co-Title Sponsor, Hevolution, Chip Wilson, CEO and Founder of SOLVE FSHD, Canada

Overview of Prize, Competition Guidelines, Qualifying Submissions:
Jessica Yoon, Prize Manager, XPRIZE Healthspan, USA and Dr. Jamie Justice, Executive Director, XPRIZE Healthspan and EVP Health Domain, USA

Alex Zhavoronkov, Insilico Medicine, USA, presents at the 11th Aging Research and Drug Discovery meeting: Methylation Clocks and AI Life Models as Sources of Therapeutic Targets

Gil Blander, InsideTracker, USA, presents at the 11th Aging Research and Drug Discovery meeting: Long-Term Improvements in Key Biomarkers in a Real-World Cohort of Digital Health Platform Users

Session Presenters:
Dr. Yianni Psaltis, Managing Director, Exponential Ventures
Dr. Alex Colville, Co-Founder and General Partner, Age1
Marc Bernegger, Founding Partner, Maximon
Lada Nuzhna, Director, Impetus Grants
Dr. Mehmood Khan, CEO of Hevolution Foundation, Saudi Arabia

Hal Gunn, Qu Biologics, Canada, presents at the 11th Aging Research and Drug Discovery meeting: Living Longer and Healthier by Training Innate Immunity: Transforming Aging

Saul Villeda, University of California, USA, presents at the 11th Aging Research and Drug Discovery meeting: Blood-based approaches to counter brain aging

Johan Luthman, Lundbeck, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: Bezisterim What can be done about the aging brain? - New advances in pharmatherapy

Maiken Nedergaard, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: The night life of the brain

Chris Reading, BioVie, USA, presents at the 11th Aging Research and Drug Discovery meeting: Bezisterim Effects on Biological Age, Alzheimer’s Epigenetics, and Neurologic Assessments

Jennifer Garrison, Buck Institute, USA, presents at the 11th Aging Research and Drug Discovery meeting: Engineering Healthy Aging in Females

Martin Lauritzen, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: Transport at the blood-brain barrier

Christina Camell, Institute on the Biology of Aging and Metabolism, USA, presents at the 11th Aging Research and Drug Discovery meeting: Targeting immune function in older organisms

Scotch McClure, Maxwell Biosciences, USA, presents at the 11th Aging Research and Drug Discovery meeting: Is Aging Contagious? Reviewing the known pathogenic drivers of degenerative aging

Anders M. Näär, University of California, Berkeley, USA, presents at the 11th Aging Research and Drug Discovery meeting: RNA Medicines to Increase Healthspan: Therapeutic Targeting of Pathological RNAs in Aging-Related Diseases

Georg Nebgen, LongeVC, Switzerland, presents at the 11th Aging Research and Drug Discovery meeting: Value Inflection Points: Successful Balancing of Expectations & Reality

Lykke Sylow, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: Preserving muscle mass for healthy aging: Old tricks and new targets

Collin Ewald, Novartis, Switzerland, presents at the 11th Aging Research and Drug Discovery meeting: Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age

Marie Kveiborg, Novo Nordisk Foundation, Denmark, presents at the 11th Aging Research and Drug Discovery meeting: The Novo Nordisk Foundation – from basic biomedical discoveries to clinical translation, through strategic partnering

Laura Goetz, XPRIZE Healthcare, presents at the 11th Aging Research and Drug Discovery meeting - Longevity Medicine Track: n=1 trials in the clinic

Thomas Rando, UCLA, USA, presents at the 11th Aging Research and Drug Discovery meeting - Longevity Medicine Track: Stem cell aging: From basic science to lifestyle interventions for rejuvenation

Nir Barzilai, Albert Einstein College of Medicine, USA, presents at the 11th Aging Research and Drug Discovery meeting - Longevity Medicine Track: From geroscience to gerotherapeutics

James Kirkland, Robert and Arlene Kogod Center on Aging, USA, presents at the 11th Aging Research and Drug Discovery meeting - Longevity Medicine Track: Potential Clinical Studies of Gerodiagnostic Biomarkers and Gerotherapeutics in Healthy Longevity Clinics

Michael Ringel, BCG, USA, presents at the 11th Aging Research and Drug Discovery meeting - Longevity Medicine Track: Why we age

Elena Bonfiglioli, Microsoft, GM healthcare, Global, presents at the 11th Aging Research and Drug Discovery meeting - Longevity Medicine Track: Microsoft Healthcare in AI precision medicine

Shahaf Peleg, Group Leader FBN Dummerstorf, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Upgrading to Animal Models 2.0

Tae Seok Moon, J. Craig Venter Institute, USA, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Systems and synthetic biology: constructing smart and programmable microbes and microbiota to address global problems

Lingyan Shi, University of California, San Diego, USA, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Metabolic nanoscopy for studying aging and diseases

Ed Boyden, MIT, USA, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Tools for Analyzing, Controlling, and Simulating Biological Systems

Emad Moeendarbary, University College London, UK, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Mechanobiology of ageing and emergence of microfluidic organs-on-chips technologies

Jacob Hanna, Weizmann Institute of Science, Israel, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Synthetic Ex Utero Embryogenesis: from Naive Stem Cells to bona fide Embryo Models

João Pedro Magalhães, University of Birmingham, UK, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Winter is coming: Cryopreservation as an emerging longevity technology

Neal Amin, Stanford University, USA, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Advancing neural replacement using stem cell-derived organoids

Anders Sandberg, Institute of Futures Studies, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Brain Emulation

Georg Fuellen, Institute for Biostatistics and Informatics in Medicine and Ageing Research in Rostock, Germany, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Validation Requirements for AI-based Intervention-Evaluation in Aging and Longevity Research and Practice

Indra John Heckenbach, University of Copenhagen, Denmark, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Deep Learning of Cellular Senescence to Predict Cancer Risk

Jing-Dong Jackie Han, Peking-Tsinghua Center for Life Sciences, China, presents at the 11th Aging Research and Drug Discovery meeting - Emerging Science & Technologies Workshop: Ethnic-Related Aging Rate Modification