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Alzheimer’s Disease: Are we missing key pieces of the puzzle?
May 12 @ 8:00 am - 5:00 pm

Alzheimer’s disease remains a mystery, but are we overlooking crucial factors?
This webinar brings together experts to explore cognitive decline, key pathological features like amyloid plaques and tau tangles, neuropathology, and potential autoimmune connections. It will also unveil a new theory on Polyamine Dysregulation and Nucleolar Disruption, offering a fresh perspective on neurodegeneration.
Objectives:
- Examine the key symptoms and pathological features of Alzheimer’s disease, including cognitive decline, amyloid plaques, tau tangles, and neuroinflammation.
- Evaluate the role of interdisciplinary research in advancing our understanding of Alzheimer’s disease and identifying new research directions.
- Analyze the potential links between autoimmune processes and neurodegenerative disorders, with a focus on Alzheimer’s disease.
- Assess how targeting nucleolar dynamics and polyamine metabolism could serve as novel therapeutic strategies for Alzheimer’s disease and related disorders.
Agenda:
1. Welcome & Introduction (5 min)
2. Setting the Context: Understanding Alzheimer’s Disease (30 min)
- Speaker 1: Neuropsychology Perspective
- Symptoms of Alzheimer’s disease
- Cognitive decline and behavioral changes
- Speaker 2: Biological/Neuropathological Perspective
- Biological mechanisms and pathological features (e.g., amyloid plaques, tau tangles, inflammation, immune system)
- Connecting pathology to interdisciplinary research
- Autoimmune Theories & Links to Neurodegeneration
- Speaker 3: New Theory- Polyamine Dysregulation and Nucleolar Disruption in Alzheimer’s Disease (30 min)
- Alternative views on nucleolar dysfunction
- Polyamine imbalances and neurodegeneration
- Therapeutic and translational insights
3. Discussion and Q&A (20 min)
- Moderator-led discussion
- Audience questions and expert responses
Marit Ruitenberg
Leiden University, the Netherlands
Marina Jendrach
Privatdozen, Charité Universitätsklinik Berlin
Wesley Brooks
Courtesy Assistant Professor, (University of South Florida, Chemistry), Associate Editor, (Journal of Translational Autoimmunity)