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X-WR-CALDESC:Events for DEMENTIA RESEARCHER
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DTSTART:20250330T010000
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DTSTART;TZID=Europe/London:20251218T150000
DTEND;TZID=Europe/London:20251218T154500
DTSTAMP:20260809T202542
CREATED:20251203T104444Z
LAST-MODIFIED:20251203T104444Z
UID:10002010-1766070000-1766072700@www.dementiaresearcher.nihr.ac.uk
SUMMARY:How abnormal tau impacts mitochondrial function in neurons
DESCRIPTION:Swiss Network for Dementia Research Webinar by Dr. Amandine Grimm\, University of Basel. \nTauopathies such as Alzheimer’s disease are characterized by progressive neuronal dysfunction\, in part driven by impaired mitochondrial bioenergetics and dynamics. \nIn this webinar\, Dr. Grimm will start by presenting how abnormal tau impacts mitochondrial function in neurons. Then\, she will present recent findings from two complementary studies conducted by her group. The first explores how abnormal tau protein influences intercellular mitochondrial transfer between astrocytes and neurons. The second study investigates the therapeutic potential of mitochondrial transplantation\, showing that the exogenous delivery of healthy astrocytic mitochondria enhances bioenergetics and promotes neurite outgrowth in tauopathy neurons. \nTogether\, these findings shed light on the mechanistic link between tau and mitochondrial communication\, and open novel avenues for cell-based mitochondrial therapies in neurodegenerative disease. \nFind out more
URL:https://www.dementiaresearcher.nihr.ac.uk/event/how-abnormal-tau-impacts-mitochondrial-function-in-neurons/
LOCATION:Online\, United Kingdom
CATEGORIES:Lecture
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