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DTSTART;VALUE=DATE:20260112
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SUMMARY:Human Amyloid Imaging Conference
DESCRIPTION:The overall goal of the Human Amyloid Imaging conference is to support active communication and collaboration between academic and industry scientists doing cutting-edge research in human imaging of amyloid-beta\, tau\, and/or other biomarkers that pertain to Alzheimer’s disease and related disorders. \nHAI 2026 will be held once again in beautiful San Juan\, Puerto Rico\, at the Puerto Rico Convention Center\, from Monday\, January 12 through Wednesday\, January 14. \nThe meeting will also provide related perspectives from neuropathology\, neurochemistry\, psychology\, neurology\, molecular imaging\, clinical trials\, and biomarker research. \n\nAttendees will have the opportunity to review the basic\, fundamental principles of PET imaging of amyloid and tau radiotracers. This includes radiotracer synthesis\, PET acquisition and data processing (e.g.\, application of corrections for the partial volume effect\, co-registration with structural data). Aspects of radiotracer discovery and optimization and first in human applications are other important topics.\nData analysis procedures discussed will include voxel-based and region-based imaging approaches\, masking for vulnerable regions\, evaluation of reference regions or standards\, choice of statistical procedures and specific use of control groups from older age groups. Important topics include data harmonization methods for imaging and biofluid biomarkers.\nNeuropathology concepts will be discussed in the context of applications that include further characterization of neurodegeneration in AD and related disorders\, disease subtypes\, disease staging\, and risk factors. Additional investigations of importance include neuropathological evaluation of PET radiotracer properties (e.g.\, distribution\, localization of specific and off-target binding) and correspondence between antemortem PET and postmortem measures.\nBiofluid biomarker development\, validation\, and application in AD and related disorders will be discussed. This will include efforts to understand relationships across established and emergent biofluid biomarkers and comparison of these outcomes to amyloid and tau PET measures.\nThe concept of biomarker positivity will continue to be extensively discussed\, and the attendees should be able to characterize the advantages and disadvantages of both dichotomized and continuous variable approaches to imaging and non-imaging biomarkers relevant to the human amyloid imaging field and with respect to specific purposes or intended uses of the outcome.\nAttendees will have the opportunity to evaluate amyloid and tau data in specific clinical and clinical research contexts\, including review of typical findings in AD dementia\, mild cognitive impairment due to AD\, and in clinically normal individuals. This includes further elucidation of factors that underlie relationships between amyloid and tau deposition\, cognitive decline\, and dementia progression that provide a more informed understanding of individual patient trajectories. These efforts will also be related to familial forms of the disease\, Down Syndrome\, and to non-AD processes (i.e.\, fronto-temporal lobar degeneration and Lewy Body dementia). Further study of “real world” research participants will be discussed that includes people from diverse\, ethnic and/or racial minority\, and disadvantaged groups.\nParticular attention will be given to the assessment of longitudinal amyloid and tau PET data as it relates to methods of analysis and comparison to other domains of data\, including structural and functional brain imaging data\, and clinical and cognitive outcomes. An ongoing topic of importance is the relative value of PET versus other detection strategies (e.g.\, MRI volumetry and biofluid biomarkers).\nAttendees will also continue to have the opportunity the better understand methodology that can be used to optimize participant selection and conduct of AD therapeutic trials. Important topics relate to improved understanding of how in vivo metrics (imaging and non-imaging) and cognition change in response to AD therapeutic treatment (cross-sectionally and longitudinally) and how to better identify those most vulnerable to treatment side-effects\, such as anti-amyloid related imaging abnormalities.\n\nFind out more and register
URL:https://www.dementiaresearcher.nihr.ac.uk/event/human-amyloid-imaging-conference/
CATEGORIES:Conference
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DTSTART;VALUE=DATE:20260128
DTEND;VALUE=DATE:20260131
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SUMMARY:127th British Neuropathological Society meeting
DESCRIPTION:The View\, Royal College of Surgeons of England\, Lincoln’s Inn Fields\, London \nThe British Neuropathological Society is delighted to invite you to join the 127th British Neuropathological Society meeting. \nThe next Annual Scientific Meeting of the British Neuropathological Society will be held from 28th – 30th January 2026.  We will return for the fourth year in a row to The View in Lincoln’s Inn Fields\, in the heart of London.  Part of The Royal College of Surgeons of England\, The View is a modern purpose-built conference and event space with spectacular views of London. \nSYMPOSIUM Wednesday 28th January\nTHEME – From Threads to Therapies: The Tau Story in Neurodegeneration. \nSPEAKERS \n\nProf Michel Goedert (MRC Laboratory of Molecular Biology\, University of Cambridge)\nDr Marc Busche (UK Dementia Research Institute at UCL and Honorary Consultant Psychiatrist at Queen Square National Hospital for Neurology and Neurosurgery)\,\nDr Steph Fowler (University of Oxford)\nProf Henrik Zetterberg (UCL Queen Square Institute of Neurology)\n\n\nDOROTHY RUSSELL MEMORIAL LECTURE Wednesday 28th January\nSpeaker – Prof Tamas Revesz\n\nCLINICAL UPDATE SESSION Friday 30th January\nTheme – Muscle and Nerve pathology \nSPEAKERS \n\nGuiseppe Lauria (University of Milan)\nSebastian Bradner (UCL)\nAshirwad Merve (GOSH/UCL)\n\n**Full meeting programme to follow** \n\nCALL FOR ABSTRACTS\nAbstracts are invited for consideration as orals\, posters and posters with flash talk.  The submission deadline is Friday 31st October 2025 and notifications will be sent out in early-December. \nPlease click here to submit your abstract. \nMEETING REGISTRATION\nPlease click here to register now.
URL:https://www.dementiaresearcher.nihr.ac.uk/event/127th-british-neuropathological-society-meeting/
LOCATION:Royal College of Surgeons\, Nicolson Street\, Edinburgh\, Scotland\, EH8 9DW\, United Kingdom
CATEGORIES:Conference
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