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X-WR-CALDESC:Events for DEMENTIA RESEARCHER
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DTSTART:20260329T010000
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DTSTART;TZID=Europe/London:20260422T140000
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DTSTAMP:20260830T184822
CREATED:20260327T111108Z
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SUMMARY:NAMs Technology Partn3Ring webinar
DESCRIPTION:The first NAMs webinar will include presentations from researchers working across invertebrate models as partial replacements for the use of mammals\, human-relevant microphysiological models\, drug efficacy and drug/consumer product toxicity testing. \nEarly drug screening with C. elegans: A 3Rs-aligned approach \nSara Leighton (Magnitude Biosciences Limited)\n•    High-throughput C. elegans platform\, delivering scalable and predictive insights on drug efficacy\, safety and mechanism of action.\n•    Seeking collaborators to further qualify screening platform and provide access to comparator datasets. \nFrom model to method: Validating C. elegans-based DART assay towards regulatory use \nEva Martini (Nagi Bioscience)\n•    Providing human relevant whole organism toxicity data that can replace early mammalian screens.\n•    Seeking collaborators for new toxicology use cases\, cross‑species comparison\, and standardisation towards regulatory readiness. \nTitle TBC\nMargaret Magdesian (Ananda Devices)\n•    Developing human iPSC‑based neuro and neuromuscular assays towards replacing animal use in neurotoxicity assays.\n•    Seeking partners to benchmark and expand applications\, including exploring incorporation into regulatory workflows. \nTitle TBC\nVitaliy Khutoryanskiy (University of Reading)\n•    Developing invertebrate assays that can replace early-stage mammalian studies in toxicity\, irritation\, infection and formulation screening.\n•    Seeking collaborators interested in co-developing and qualifying the invertebrate-based assays for broader application and increased translational relevance. \n\nRegister
URL:https://www.dementiaresearcher.nihr.ac.uk/event/nams-technology-partn3ring-webinar/
LOCATION:Online
CATEGORIES:Online
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ORGANIZER;CN="NC3Rs":MAILTO:enquiries@nc3rs.org.uk
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