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DTSTART;VALUE=DATE:20260422
DTEND;VALUE=DATE:20260423
DTSTAMP:20260506T010601
CREATED:20260327T113708Z
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SUMMARY:Replacing in vivo models with complex cellular systems
DESCRIPTION:As regulatory expectations evolve towards inclusion of new approach methodologies (NAMs) in safety assessment and the scientific community focuses on mechanism‑driven discovery research\, this event from ELRIG’s UK Forum offers a timely forum to explore emerging replacement technologies that deliver greater physiological relevance to human biology. \nThrough expert talks\, interactive discussions and technology demonstrations\, attendees will gain a clear understanding of how next‑generation models\, including organoids\, microphysiological systems and co‑culture platforms\, can be integrated into drug discovery pipelines. \nThis one‑day meeting will showcase cutting‑edge advances in complex cellular systems\, animal‑replacement technologies\, and new approach methodologies (NAMs) that are reshaping translational research and reducing reliance on traditional in vivo models. As regulatory expectations evolve and the scientific community accelerates toward human‑relevant\, mechanism‑driven discovery\, the event offers a timely forum for delegates to explore emerging technologies that deliver greater physiological relevance\, improved predictivity\, and enhanced ethical sustainability. Through expert talks\, interactive discussions\, and technology demonstrations\, attendees will gain a clear understanding of how these next‑generation models\, including organoids\, microphysiological systems\, and co‑culture platforms\, can be integrated into discovery pipelines today. \nDelegates will leave with three key learnings: \n\nA critical view of the latest complex cellular\, NAM\, and animal‑replacement systems and their translational value.\nPractical strategies for replacing or reducing animal models while maintaining scientific robustness.\nActionable insights on implementation\, including assay design\, validation considerations\, and operational challenges.\n\nThe programme will deliver: \n\nA critical view of the latest complex cellular models\, NAMs and non-animal technologies and their translational value.\nPractical strategies for replacing or reducing animal models while maintaining scientific robustness.\nActionable insights on implementation\, including assay design\, validation considerations and operational challenges.\n\nAbout ELIRG\nELRIG is a not-for-profit organisation bringing together the global life science and drug discovery industry at open-access\, free-to-attend events. Find out more: elrig.org. \nDr Cathy Vickers (NC3Rs Head of Innovation) is a member of the ELRIG Science Committee and a Director of this ELRIG UK Forum\, alongside Drs Emma Shepard (Aston University)\, Paul Roach (Loughborough University) and Eric Hill (Loughborough University). \n\nRegister
URL:https://www.dementiaresearcher.nihr.ac.uk/event/replacing-in-vivo-models-with-complex-cellular-systems/
LOCATION:Loughborough University\, Epinal Way\, Loughborough\, LE11 3TU\, United Kingdom
CATEGORIES:Training
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