CRISPR molecular & cell biologist

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Website UniofOxford University of Oxford

Closing date: 29th September 2021


Target Discovery Institute, NDMRB, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7FZ

Grade 7: £32,817 – £40,322 with a discretionary range to £44,045 per annum

We are seeking a postdoctoral scientist with expertise in CRISPR engineering for editing in cellular models and genome screening, at the University of Oxford’s Target Discovery Institute (TDI).

You will be based in the Cellular Screening Facility but will also be integrated into the ARUK Oxford Drug Discovery Institute (ODDI), two teams that are co-located in the TDI.  Your primary role will be to use CRISPR editing techniques to validate targets in cellular models of neurodegenerative disease. You will be responsible for organising and maintaining relevant plasmid libraries, creating, titreing, curating lentivirus stocks and creating sub-pools as necessary.

It is essential that you have a PhD in molecular/cell biology, biochemistry or a related subject, together with professional experience in a research laboratory. You will need in-depth knowledge of molecular biology techniques, especially advanced cloning (e.g. Golden Gate, Gibson assembly) and PCR (e.g. site-directed mutagenesis), as well as biochemical and cell biological techniques (e.g. western blotting, immunofluorescence, qRT-PCR). Experience with CRISPR/Cas9 editing or screening is required. You must be highly organised, have an excellent attention to detail and the ability to work flexibly to manage your time and a varied workload under pressure to meet deadlines.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This post is offered full-time on a fixed term contract until 30 October 2024, and is funded by Alzheimer’s Research UK.

Please quote 153072 on all correspondence. Only applications received before 12.00 noon on 29 September 2021 will be considered.

Contact Person : NDM Recruitment Team Vacancy ID : 153072
Contact Phone : 01865 287870 Closing Date & Time : 29-Sep-2021 12:00
Contact Email :

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