Project Scientist for (MODEL-AD)

Reading Time: 3 minutes
no comments

Website UofCalifornia University of California

Closing date: 28th April


UC-MIND has an opportunity for a project scientist to join the UCI Model Organism Development and Evaluation for Late-onset Alzheimer’s Disease (MODEL-AD) Disease Modeling Project (DMP). MODEL-AD is an NIA/NIH-funded multi-project, multi-institutional grant whose goal is to produce the next generation of mouse models for late-onset AD and develop new therapeutic targets.

Under the direction of Grant MacGregor, professor and director of the UCI Transgenic Mouse Facility, the successful applicant will be responsible for leading daily operations of a large-scale project to generate improved mouse models of late-onset Alzheimer’s disease. The project involves use of contemporary methods of genome engineering in mice, combined with assisted reproduction and germplasm and pre-implantation embryo cryopreservation, large colony inventory management, and monitoring health and aging of the colony. Job also includes administrative duties on exporting mouse models to the Jackson Laboratory, and supervising scientific research assistant(s) and student research assistant(s).

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being up-to-date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.


Candidates with a doctoral degree in mouse developmental genetics and a minimum of five to seven years experience are encouraged to apply. Preference will be given to candidates with demonstrated experience in: mouse germplasm and embryo cryopreservation; in vitro fertilization using mouse germplasm; surgical transfer of pre-implantation embryos to recipient mice; mouse breeding and husbandry, including C-section and fostering and development of PCR-based genotyping assays including TaqMan, rhAMP or similar fluorescent-probe-based assays, and the use of automated capillary electrophoresis. Eligible candidates should also have experience in genome analysis, database development and management, and strong record-keeping skills. Excellent supervisory skills, the ability to work independently, including setting team and personal goals and meeting deadlines, and strong communication skills are essential.


Please submit a letter of interest, curriculum vitae which should include a record of research experience and the names of three references before April 28, 2023, to:

Document requirements

Apply link:

To apply for this job please visit

Translate »