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Endosomal-lysosomal network dysfunction in neurodegeneration

September 1 - September 4

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The 2026 Harden Conference on ‘Endosomal-lysosomal Network Dysfunction in Neurodegeneration’ will be the first focused UK based conference bringing together world-leading researchers in endosomal-lysosomal biology and neurodegenerative research.

Alterations in the endosomal-lysosomal system are emerging as key features underlying pathogenesis in several neurodegenerative and neurological disorders, and has generated significant interest as to whether this pathway can be targeted for early-stage diagnostics and therapeutics.

This meeting aims to generate new insight into the latest advances in the endosomal-lysosomal system to enhance the rate of discovery in neurodegenerative research. Researchers from all career stages across the academic and industrial sectors will come together to exchange ideas, share cutting edge methodologies and technical knowledge, and formulate new collaborations. This meeting will also facilitate the establishment of an ongoing network of researchers interested in the endosomal-lysosomal system to push forward diagnostic and therapeutic strategies in this rapidly moving area of research.

Session Topics:
Session 1: Endosomal-lysosomal membrane organisation
Session 2: Organellar Crosstalk between the endosomal lysosomal network
Session 3: Cutting edge methodologies for investigating the endosomal lysosomal network
Session 4: Endosomal-lysosomal dysfunction in neurodegeneration
Session 5: Proteostasis and protein pathology
Session 6: Non-neuronal mechanisms for neurodegeneration

Panel Sessions:
Panel Discussion: Biomarkers and therapeutic targets/strategies for the endo-lysosomal pathway
Panel Dicussion: Experimental assessment of endocytic biology – pitfalls, new and better methods
Career Development sessions

Programme Coordinators:
Natalie Connor-Robson, Cardiff University
Pete Cullen, Bristol University
Kirsty McMillan, University of Liverpool

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Register to Attend

Venue

Solent Hotel & Spa
Rookery Avenue, Whiteley
Fareham, Hampshire PO15 7AJ United Kingdom
+ Google Map
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