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Dementia Researcher 3.4K

Imaging Alzheimer’s Disease in Down Syndrome

Dementia Researcher 07/08/2026 11:01 am

Emma Williams and Sue Williams discuss their work.

Emma and Sue have a job title that stops conversations. Public Advisor Researcher. They did not know what it meant when they applied, and two years on they are still explaining it to other people, including to public advisors who now think they have gone over to the other side. Both came to it through caring, Emma for her Mam who had frontotemporal dementia, Sue for her father and later for a close friend. Now they write topic guides, recruit participants, run interviews and work on the analysis, while still being carers themselves. In this blog they set out what the role actually involves, what it costs them, and what an early career researcher can do to make a Public Advisor Researcher useful rather than decorative.

https://www.dementiaresearcher.nihr.ac.uk/blog-what-is-a-public-advisor-researcher/
--

Emma Williams and Sue Williams are Public Advisor Researchers at the University of Liverpool. Both came to dementia research through their personal experiences of supporting family members living with dementia and related conditions. They now use that lived experience alongside their growing research expertise to help shape dementia research, contributing to study design, recruitment, interviews and data analysis. Their work focuses particularly on ensuring the experiences of people affected by dementia are properly represented in research and in efforts to improve dementia care.

https://bsky.app/profile/denpru-qm.bsky.social
--

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Emma Williams and Sue Williams discuss their work.

Emma and Sue have a job title that stops conversations. Public Advisor Researcher. They did not know what it meant when they applied, and two years on they are still explaining it to other people, including to public advisors who now think they have gone over to the other side. Both came to it through caring, Emma for her Mam who had frontotemporal dementia, Sue for her father and later for a close friend. Now they write topic guides, recruit participants, run interviews and work on the analysis, while still being carers themselves. In this blog they set out what the role actually involves, what it costs them, and what an early career researcher can do to make a Public Advisor Researcher useful rather than decorative.

https://www.dementiaresearcher.nihr.ac.uk/blog-what-is-a-public-advisor-researcher/
--

Emma Williams and Sue Williams are Public Advisor Researchers at the University of Liverpool. Both came to dementia research through their personal experiences of supporting family members living with dementia and related conditions. They now use that lived experience alongside their growing research expertise to help shape dementia research, contributing to study design, recruitment, interviews and data analysis. Their work focuses particularly on ensuring the experiences of people affected by dementia are properly represented in research and in efforts to improve dementia care.

https://bsky.app/profile/denpru-qm.bsky.social
--

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YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLjh0VGl0eTdxOWFN

Emma & Sue Williams - A what? A Public Advisor Researcher? You may well ask…

Dementia Researcher 06/08/2026 10:05 am

Emily Spencer narrates her blog written for Dementia Researcher.

With her her viva date set and every working hour going into her thesis, Emily has also just returned to conference season for the first time since her maternity leave in 2023. At the International Psychogeriatric Association Congress in the Netherlands she gave an oral presentation on her conversation analytic study of advance care planning conversations between GPs, people with dementia, and their carers. In this blog she works through the layers of worry that came before it: pitching a niche method to a general audience, trusting the tech to play her video clips, presenting with poor eyesight that rules out speaker notes, and the dread of audience questions, all with her primary supervisor watching. What actually happened surprised her, and she explains why the experience has given her confidence for future talks and for defending her thesis. A good listen for anyone who has ever stood at a lectern convinced their work is too niche to interest anyone.

https://www.dementiaresearcher.nihr.ac.uk/blog-overcoming-academic-conference-presentation-anxiety/
--

Emily Spencer is a PhD Student at University College London looking at improving how GPs communicate with people with dementia and their family carers about their future care. Emily previous had a 5 year career break to pursue a career as a musician, and has previously undertaken research on improving the care people with dementia receive from their GP practice, as well as end-of-life and palliative care provision in the community. Emily is also a new mum and will be writing about her experiences navigating motherhood and a research career.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

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Emily Spencer narrates her blog written for Dementia Researcher.

With her her viva date set and every working hour going into her thesis, Emily has also just returned to conference season for the first time since her maternity leave in 2023. At the International Psychogeriatric Association Congress in the Netherlands she gave an oral presentation on her conversation analytic study of advance care planning conversations between GPs, people with dementia, and their carers. In this blog she works through the layers of worry that came before it: pitching a niche method to a general audience, trusting the tech to play her video clips, presenting with poor eyesight that rules out speaker notes, and the dread of audience questions, all with her primary supervisor watching. What actually happened surprised her, and she explains why the experience has given her confidence for future talks and for defending her thesis. A good listen for anyone who has ever stood at a lectern convinced their work is too niche to interest anyone.

https://www.dementiaresearcher.nihr.ac.uk/blog-overcoming-academic-conference-presentation-anxiety/
--

Emily Spencer is a PhD Student at University College London looking at improving how GPs communicate with people with dementia and their family carers about their future care. Emily previous had a 5 year career break to pursue a career as a musician, and has previously undertaken research on improving the care people with dementia receive from their GP practice, as well as end-of-life and palliative care provision in the community. Emily is also a new mum and will be writing about her experiences navigating motherhood and a research career.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

Leave us a Tip
https://dementia-researcher.captivate.fm/support

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• https://www.instagram.com/dementia_researcher/
• https://www.facebook.com/Dementia.Researcher/
• https://www.twitter.com/demrescommunity
• https://www.linkedin.com/company/dementia-researcher
• https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

1 1

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLi1iT0R5X0ZOZWRZ

Emily Spencer - Overcoming Academic Conference Presentation Anxiety

Dementia Researcher 05/08/2026 12:06 pm

Adam Smith narrates his blog written for Dementia Researcher.

Publishing the paper is not the finish line, it is where the work of being read actually starts. Adam looks at what happens to research once it lands in a journal, why some of it gets noticed and a lot of it does not, and what researchers can do about that without turning themselves into a personal brand. There are some uncomfortable observations along the way about conference talks, LinkedIn, and the phrase "raising awareness", plus a couple of figures from Dementia Researcher's own channels that even he cannot fully explain. If you have ever wondered whether time spent talking about your work is time stolen from doing it, this one is worth ten minutes.

https://www.dementiaresearcher.nihr.ac.uk/blog-good-research-still-needs-an-audience/
--

Adam Smith was born in the north, a long time ago. He wanted to write books, but ended up working in the NHS, and at the Department of Health. He is now Programme Director for Dementia Researcjer at University College London. He has led a number of initiatives to improve dementia research (including this website, Join Dementia Research & ENRICH), as well as pursuing his own research interests. In his spare time he spends most of his time drinking too much coffee and squeezing technology into his house.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

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https://dementia-researcher.captivate.fm/support

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  •  https://www.instagram.com/dementia_researcher/ 
  •  https://www.facebook.com/Dementia.Researcher/
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https://www.onelink.to/dementiaresearcher

Adam Smith narrates his blog written for Dementia Researcher.

Publishing the paper is not the finish line, it is where the work of being read actually starts. Adam looks at what happens to research once it lands in a journal, why some of it gets noticed and a lot of it does not, and what researchers can do about that without turning themselves into a personal brand. There are some uncomfortable observations along the way about conference talks, LinkedIn, and the phrase "raising awareness", plus a couple of figures from Dementia Researcher's own channels that even he cannot fully explain. If you have ever wondered whether time spent talking about your work is time stolen from doing it, this one is worth ten minutes.

https://www.dementiaresearcher.nihr.ac.uk/blog-good-research-still-needs-an-audience/
--

Adam Smith was born in the north, a long time ago. He wanted to write books, but ended up working in the NHS, and at the Department of Health. He is now Programme Director for Dementia Researcjer at University College London. He has led a number of initiatives to improve dementia research (including this website, Join Dementia Research & ENRICH), as well as pursuing his own research interests. In his spare time he spends most of his time drinking too much coffee and squeezing technology into his house.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

Leave us a Tip
https://dementia-researcher.captivate.fm/support

Follow us on social media:

• https://www.instagram.com/dementia_researcher/
• https://www.facebook.com/Dementia.Researcher/
• https://www.twitter.com/demrescommunity
• https://www.linkedin.com/company/dementia-researcher
• https://bsky.app/profile/dementiaresearcher.bsky.social

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1 1

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLmFRZ201MVdxVUp3

Adam Smith - Good Research Still Needs an Audience

Dementia Researcher 31/07/2026 11:44 pm

Around 80% of women worldwide will become mothers, and pregnancy triggers the largest hormonal shift the body will ever experience. So what does it do to the brain, and does any of it last?

In this episode of XXplored, host Dr Laura Stankeviciute, University of Gothenburg is joined by Dr Magdalena Martínez-García, Scientific Director of Maternal Health at the Ann S. Bowers Women's Brain Health Initiative, University of California Santa Barbara, and Dr Laura Pritschet, an NIH funded postdoctoral scholar at the University of Pennsylvania who leads the Maternal Brain Mapping Project.

They get into the hormonal cascade that drives the whole process, what those widely reported grey matter reductions actually mean, and how one volunteer scanned 26 times from IVF to two years postpartum filled in the gap between before and after. They also take on baby brain, whether repeat pregnancies stack up in the brain, what the UK Biobank data hints at for later life dementia risk, the near total absence of miscarriage and stillbirth from this research, and where postpartum care falls short. Both guests are living through matrescence themselves while studying it, and they talk openly about what that has been like.

Key takeaways

- Pregnancy brings hormone surges into the hundreds and thousandfold, far beyond anything seen across the menstrual cycle, and sensitivity to those shifts matters more than the absolute levels.
- Grey matter reductions across pregnancy are among the most replicable findings in neuroscience, and larger reductions are linked to stronger postpartum bonding rather than damage.
- Follow-up work found some of those changes still present six years after birth, suggesting they may be long lasting or permanent.
- A second pregnancy produces the same pattern of change but less pronounced, and UK Biobank data suggests a trace of parity in the brain that levels off around four or five births.
- Baby brain gets reframed rather than dismissed: subjective reports are real, objective differences are slight and temporary, and increased cognitive load may carry later advantages.
- Miscarriage, stillbirth and abortion are almost entirely missing from maternal brain research, and both guests believe those women would be among the most motivated participants.
- Research now treats the perinatal period as a neurological transition, but healthcare has not caught up, with a single six week check standing in for what should be ongoing postpartum care.
-

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https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
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https://www.linkedin.com/company/dementia-researcher
https://www.bsky.app/profile/dementiare…archer.bsky.social
--

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--

Chapters

00:00 Welcome and why matrescence matters
02:48 Meet the guests
07:28 The hormones of pregnancy and postpartum
14:27 What grey matter reductions really mean
22:11 One brain, 26 scans
27:15 Miscarriage, stillbirth and the missing research
31:21 Fathers, partners and other caregivers
34:19 Is baby brain real?
42:32 Parity, later life and dementia risk
47:20 Two neuroscientists on their own experience
55:38 Postpartum care and what needs to change
01:02:43 What women's brain health means to us

Around 80% of women worldwide will become mothers, and pregnancy triggers the largest hormonal shift the body will ever experience. So what does it do to the brain, and does any of it last?

In this episode of XXplored, host Dr Laura Stankeviciute, University of Gothenburg is joined by Dr Magdalena Martínez-García, Scientific Director of Maternal Health at the Ann S. Bowers Women's Brain Health Initiative, University of California Santa Barbara, and Dr Laura Pritschet, an NIH funded postdoctoral scholar at the University of Pennsylvania who leads the Maternal Brain Mapping Project.

They get into the hormonal cascade that drives the whole process, what those widely reported grey matter reductions actually mean, and how one volunteer scanned 26 times from IVF to two years postpartum filled in the gap between before and after. They also take on baby brain, whether repeat pregnancies stack up in the brain, what the UK Biobank data hints at for later life dementia risk, the near total absence of miscarriage and stillbirth from this research, and where postpartum care falls short. Both guests are living through matrescence themselves while studying it, and they talk openly about what that has been like.

Key takeaways

- Pregnancy brings hormone surges into the hundreds and thousandfold, far beyond anything seen across the menstrual cycle, and sensitivity to those shifts matters more than the absolute levels.
- Grey matter reductions across pregnancy are among the most replicable findings in neuroscience, and larger reductions are linked to stronger postpartum bonding rather than damage.
- Follow-up work found some of those changes still present six years after birth, suggesting they may be long lasting or permanent.
- A second pregnancy produces the same pattern of change but less pronounced, and UK Biobank data suggests a trace of parity in the brain that levels off around four or five births.
- Baby brain gets reframed rather than dismissed: subjective reports are real, objective differences are slight and temporary, and increased cognitive load may carry later advantages.
- Miscarriage, stillbirth and abortion are almost entirely missing from maternal brain research, and both guests believe those women would be among the most motivated participants.
- Research now treats the perinatal period as a neurological transition, but healthcare has not caught up, with a single six week check standing in for what should be ongoing postpartum care.
-

Follow us on social media:

https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://www.twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
https://www.bsky.app/profile/dementiare…archer.bsky.social
--

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

Leave us a tip:
https://dementia-researcher.captivate.fm/support
--

Chapters

00:00 Welcome and why matrescence matters
02:48 Meet the guests
07:28 The hormones of pregnancy and postpartum
14:27 What grey matter reductions really mean
22:11 One brain, 26 scans
27:15 Miscarriage, stillbirth and the missing research
31:21 Fathers, partners and other caregivers
34:19 Is baby brain real?
42:32 Parity, later life and dementia risk
47:20 Two neuroscientists on their own experience
55:38 Postpartum care and what needs to change
01:02:43 What women's brain health means to us

6 1

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLnNlOUFDUlA2TWlV

XXplored - The Neuroscience of Motherhood

Dementia Researcher 31/07/2026 12:00 pm

Dr Yvonne Couch narrates her blog written for Dementia Researcher.

Do we actually need to teach Gen Z differently, or do they just need to grow up a bit? Yvonne read a Times Higher Ed article that annoyed her enough to annoy several colleagues with it, and this blog is what came out. She is not convinced by shorter lectures with cliffhangers. She is much more interested in what happens when you hand third years a hypothetical million pounds and ask them what they would do with it. Along the way she tests one of her own essay questions on ChatGPT, and finds the gap that matters.

https://www.dementiaresearcher.nihr.ac.uk/blog-pedagogy-for-gen-z/
--

Dr Yvonne Couch is a Research Fellow and Associate Professor at the University of Oxford. Yvonne studies the role of extracellular vesicles and their role in changing the function of the vasculature after stroke, aiming to discover why the prevalence of dementia after stroke is three times higher than the average. It is her passion for problem solving and love of science that drives her, in advancing our knowledge of disease. Yvonne writes about her work, academic life, and careers as she takes a new road into independent research.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

Leave us a Tip
https://dementia-researcher.captivate.fm/support

Follow us on social media:

  •  https://www.instagram.com/dementia_researcher/ 
  •  https://www.facebook.com/Dementia.Researcher/
  •  https://www.twitter.com/demrescommunity
  •  https://www.linkedin.com/company/dementia-researcher 
  •  https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

Dr Yvonne Couch narrates her blog written for Dementia Researcher.

Do we actually need to teach Gen Z differently, or do they just need to grow up a bit? Yvonne read a Times Higher Ed article that annoyed her enough to annoy several colleagues with it, and this blog is what came out. She is not convinced by shorter lectures with cliffhangers. She is much more interested in what happens when you hand third years a hypothetical million pounds and ask them what they would do with it. Along the way she tests one of her own essay questions on ChatGPT, and finds the gap that matters.

https://www.dementiaresearcher.nihr.ac.uk/blog-pedagogy-for-gen-z/
--

Dr Yvonne Couch is a Research Fellow and Associate Professor at the University of Oxford. Yvonne studies the role of extracellular vesicles and their role in changing the function of the vasculature after stroke, aiming to discover why the prevalence of dementia after stroke is three times higher than the average. It is her passion for problem solving and love of science that drives her, in advancing our knowledge of disease. Yvonne writes about her work, academic life, and careers as she takes a new road into independent research.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

Leave us a Tip
https://dementia-researcher.captivate.fm/support

Follow us on social media:

• https://www.instagram.com/dementia_researcher/
• https://www.facebook.com/Dementia.Researcher/
• https://www.twitter.com/demrescommunity
• https://www.linkedin.com/company/dementia-researcher
• https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

1 1

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLjZNTGNyS1ByNXZB

Dr Yvonne Couch - Pedagogy For Gen Z

Dementia Researcher 30/07/2026 9:56 pm

Dr Lindsey Sinclair narrates her blog written for Dementia Researcher.

Is time invested in something really time wasted if you don't win? A comment overheard at a rowing regatta set Lindsey thinking about what sport has given her career in science, beyond callouses and a dodgy shoulder. A former school sport hater turned qualified coach, Lindsey maps the anatomy of a 2000m race onto the life of a research project, from crew selection to the final push for the line, and makes the case that some of the most useful research skills are learned nowhere near a lab. There's also a lovely rowing tradition at the finish that every scientist could borrow.

https://www.dementiaresearcher.nihr.ac.uk/blog-what-sport-can-teach-science/

Dr Lindsey Sinclair is an Associate Professor and Clinical Academic in Old Age Psychiatry at the University of Southampton. Her research explores the relationship between depression and dementia, combining lab work with epidemiology and genetics. Clinically, she works with older adults experiencing a wide range of mental health problems. Outside of work, she’s a keen baker and runner, and has a particular talent for creating ambitious birthday cakes.

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Follow us on social media:

  •  https://www.instagram.com/dementia_researcher/ 
  •  https://www.facebook.com/Dementia.Researcher/
  •  https://www.twitter.com/demrescommunity
  •  https://www.linkedin.com/company/dementia-researcher 
  •  https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

Dr Lindsey Sinclair narrates her blog written for Dementia Researcher.

Is time invested in something really time wasted if you don't win? A comment overheard at a rowing regatta set Lindsey thinking about what sport has given her career in science, beyond callouses and a dodgy shoulder. A former school sport hater turned qualified coach, Lindsey maps the anatomy of a 2000m race onto the life of a research project, from crew selection to the final push for the line, and makes the case that some of the most useful research skills are learned nowhere near a lab. There's also a lovely rowing tradition at the finish that every scientist could borrow.

https://www.dementiaresearcher.nihr.ac.uk/blog-what-sport-can-teach-science/

Dr Lindsey Sinclair is an Associate Professor and Clinical Academic in Old Age Psychiatry at the University of Southampton. Her research explores the relationship between depression and dementia, combining lab work with epidemiology and genetics. Clinically, she works with older adults experiencing a wide range of mental health problems. Outside of work, she’s a keen baker and runner, and has a particular talent for creating ambitious birthday cakes.

Leave us a Tip
https://dementia-researcher.captivate.fm/support

Follow us on social media:

• https://www.instagram.com/dementia_researcher/
• https://www.facebook.com/Dementia.Researcher/
• https://www.twitter.com/demrescommunity
• https://www.linkedin.com/company/dementia-researcher
• https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

1 1

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLkVrSVFWVFRmYlFV

Dr Lindsey Sinclair - What Sport Can Teach Science

Dementia Researcher 29/07/2026 2:25 pm

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