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The Integrative Neuromodulatory Subcortical Systems (INSS) 2025 Meeting
July 17 - July 18

We are delighted to welcome you to the inaugural Integrative Neuromodulatory Subcortical Systems (INSS) 2025 meeting. Hosted by the Neuromodulatory Subcortical Systems (NSS) Professional Interest Area (PIA) of the International Society to Advance Alzheimer’s Research and Treatment (ISTAART), in collaboration with the Sleep and Circadian Rhythms PIA, this meeting brings together researchers and clinicians to explore the critical role of the NSS in neurodegenerative diseases.
This network of conserved nuclei modulates behavior, cognition, and sleep-wake cycles, while also exhibiting increased vulnerability in the earliest stages of Alzheimer’s disease and contributing to the sleep-mediated clearance of associated proteinopathies.
This two-day hybrid event in Boston, made possible through the support of ISTAART, aims to bridge gaps in understanding the NSS’ contributions to neurodegeneration and related processes by integrating diverse perspectives across disciplines, career stages and global regions. Featuring keynote lectures, presentations on emerging topics, panel discussions, round table sessions, and networking opportunities, the INSS meeting seeks to inspire new ideas, foster collaboration, and advance research in this vital and rapidly evolving field. To participate, please register and submit your abstract. In-person spots are limited, so early registration is encouraged. Thank you for joining us in shaping the future of NSS research!
Key dates and Information
The INSS 2025 Meeting will take place on July 17-18, 2025, in a hybrid format, offering both in-person sessions in Boston, MA, USA, and virtual participation options.
Registration and Abstract submission is open till March 31st, 2025 (11:30pm EST). Please note that you can also join the INSS 2025 Meeting without submitting an abstract. Please navigate to the Registration and Abstract Submission page for more details.
PROGRAM
REGISTRATION
ABSTRACT SUBMISSIONS
Travel information and Visa
Please stay tuned for further details, which will be announced soon.
Accommodations
The two closest accommodation options to the Martinos Center/Charlestown Navy Yard are the Marriott Residence Inn at Tudor Wharf (https://www.marriott.com/en-us/hotels/bostw-residence-inn-boston-harbor-on-tudor-wharf/overview/) and the Courtyard Boston Downtown/North Station (https://www.marriott.com/en-us/hotels/bosne-courtyard-boston-downtown-north-station/overview/). Both offer discounted rates and are conveniently located near a free MGH/MGB shuttle bus stop, providing service to the Charlestown Navy Yard every 15 minutes during the day and every 30 minutes in the evening. For details on applying discounts and exploring other (discounted) accommodations, please visit the following website: https://education.martinos.org/accommodations/
NSS PIA
All our past and upcoming activities can be followed at: https://training.alz.org/research-webinars. Please follow the NSS PIA on Twitter/X (@NSS_PIA) and LinkedIn to receive updates on recent publications, our activities and plans!
Questions
Still pending questions? Please do not hesitate to email nengels@mgh.harvard.edu.
Funding for this meeting was made possible in part by the ISTAART Grant Program for Conferences and Convenings (award ID: IGPCC-D-1321705), and Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART), through the Neuromodulatory Subcortical Systems Professional Interest Area (PIA). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Alzheimer’s Association; nor does mention by trade names, commercial practices, or organizations imply endorsement by the Alzheimer’s Association.