Neurofilament in Blood Foretells Early Onset Alzheimer’s
A paper published online on the 21st January in Nature Medicine finds that in familial Alzheimer’s disease, blood levels of neurofilament light (NfL) rise 16 years before the predicted age…
A paper published online on the 21st January in Nature Medicine finds that in familial Alzheimer’s disease, blood levels of neurofilament light (NfL) rise 16 years before the predicted age…
In the January 11 Science, Yigong Shi, Tsinghua University, Beijing, and colleagues present a high-resolution cryo-electron microscopy structure of γ-secretase enfolding a fragment of APP. Find out more on their work from this post on the Alz Forum.
Researchers from University College London have strengthened the case that certain medical procedures can transfer amyloid pathology between people.
Latest on investigational treatments in the pipeline. Two-part series on recent results published at the CTAD Conference from Pat McCaffrey for the Alz Forum.
Merck shook the field with news that people on verubecestat scored worse than those on placebo – find out more in this post from AlzForum
Developing computational algorithms & machine-learning techniques, to transform cross-sectional imaging data to a longitudinal picture and reconstruct the sequence of disease progression.
Many genetic variants predispose to Alzheimer’s disease, but exactly how remains a mystery.
In AD, tau tangles correlate closely with neurodegeneration, but how they work their mischief remains unclear… or does it?
For everything there is a season—perhaps even cognition?
Check out the “booths” in this new section of the AlzForum to learn about products and services that could accelerate your research.
https://www.alzforum.org/news/research-news/does-daytime-drowsiness-foreshadow-av-accumulation