All the events here are relevant to people working in dementia research. If you would like to add your own you can submit an event
Replacing in vivo models with complex cellular systems
April 22
As regulatory expectations evolve towards inclusion of new approach methodologies (NAMs) in safety assessment and the scientific community focuses on mechanism‑driven discovery research, this event from ELRIG’s UK Forum offers a timely forum to explore emerging replacement technologies that deliver greater physiological relevance to human biology.
Through expert talks, interactive discussions and technology demonstrations, attendees will gain a clear understanding of how next‑generation models, including organoids, microphysiological systems and co‑culture platforms, can be integrated into drug discovery pipelines.
This one‑day meeting will showcase cutting‑edge advances in complex cellular systems, animal‑replacement technologies, and new approach methodologies (NAMs) that are reshaping translational research and reducing reliance on traditional in vivo models. As regulatory expectations evolve and the scientific community accelerates toward human‑relevant, mechanism‑driven discovery, the event offers a timely forum for delegates to explore emerging technologies that deliver greater physiological relevance, improved predictivity, and enhanced ethical sustainability. Through expert talks, interactive discussions, and technology demonstrations, attendees will gain a clear understanding of how these next‑generation models, including organoids, microphysiological systems, and co‑culture platforms, can be integrated into discovery pipelines today.
Delegates will leave with three key learnings:
- A critical view of the latest complex cellular, NAM, and animal‑replacement systems and their translational value.
- Practical strategies for replacing or reducing animal models while maintaining scientific robustness.
- Actionable insights on implementation, including assay design, validation considerations, and operational challenges.
The programme will deliver:
- A critical view of the latest complex cellular models, NAMs and non-animal technologies and their translational value.
- Practical strategies for replacing or reducing animal models while maintaining scientific robustness.
- Actionable insights on implementation, including assay design, validation considerations and operational challenges.
About ELIRG
ELRIG is a not-for-profit organisation bringing together the global life science and drug discovery industry at open-access, free-to-attend events. Find out more: elrig.org.
Dr Cathy Vickers (NC3Rs Head of Innovation) is a member of the ELRIG Science Committee and a Director of this ELRIG UK Forum, alongside Drs Emma Shepard (Aston University), Paul Roach (Loughborough University) and Eric Hill (Loughborough University).
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