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Synuclein Biomarkers & Neuropathology Summit 2026
April 9 @ 4:30 pm - 11:00 pm
Join co-chairs, Dr. Robert Rissman and Dr Nicholas Ashton for a focused scientific summit bringing together leading investigators, clinicians, and translational researchers to advance the future of synuclein biomarker development. This meeting will spotlight emerging hypotheses, active research programs, and key challenges limiting antemortem detection across Alzheimer’s disease–related dementias and movement disorders.
Through expert-led discussions, the summit aims to deepen understanding of synuclein pathology, ongoing therapeutic trials, and biomarker strategies to help accelerate earlier, more accurate detection.
agenda
Thursday, April 9
9:00 am-4:30 pm: Main Session
KEYNOTE PRESENTATION
Major Hypotheses in Synuclein Research Alzheimers Disease & Parkinsons Disease
Lea Grinberg, MD, PhD – Mayo Clinic
Session 1 (panel discussion): Clinical Standards for Synuclein
Moderator: Robert Rissman, PhD – Epstein Family ATRI, USC
Panelists:
Paul Aisen, MD – Epstein Family ATRI, USC
Amy Kind, MD, PhD – University of Wisconsin
James Leverenz, MD – University of Washington
Ahmad Sajjadi, MD – UC Irvine School of Medicine
Session 2: Synuclein (detecting and treating)
Moderator: Nicholas Ashton, PhD – Banner Health
Speakers:
Brian Spencer, PhD – Epstein Family ATRI, USC
Pam J. Mclean, PhD – Mayo Clinic
Duygu Tosun-Turgut, PhD – UCSF
Hartmuth Kolb, PhD – Enigma Biomedical USA
Session 3: Synuclein Proteomics
Moderator: Steve Williams, MD, PhD – Alamar Biosciences
Speakers:
Carlos Cruchaga, PhD – Washington University School of Medicine
Nicholas Ashton, PhD – Banner Health
Nicolas T. Seyfried, PhD – Emory University School of Medicine
Session 4 (panel discussion): Biomarker Therapeutics
Moderator: Sterling Johnson, PhD – University of Wisconsin
Panelists:
Joel Mathews, PhD – Ionis
Steve Williams, MD, PhD – Alamar Biosciences
Luis Concha, PhD – Amprion
Charbel Moussa, MBBS, PhD – Georgetown University Medical Center
Session 5 (panel discussion): Future Directions
Moderator: Nicholas Ashton & Robert Rissman
Panelists:
Lea Grinberg, MD, PhD – Mayo Clinic
Sterling Johnson, PhD – University of Wisconsin
Susan Landau, PhD – UC Berkeley
Steve Williams, MD, PhD – Alamar Biosciences
4:30 pm: Closing Remarks & Adjourn
Register