Print This Post
Professor Frank Gunn-Moore
Name:
Professor Frank Gunn-Moore
Job title:
Professor of Molecular Neurobiology
Place of work / study:
University of St Andrews
Area of Research:
I am known as a molecular neurobiologist who studies the cellular and biochemical development and survival of the mammalian nervous system. My approach to achieve this has been one of combining all three science disciplines.
How is your work funded:
Research Councils and Charities
Tell us a little about yourself:
I am known as a molecular neurobiologist who studies the cellular and biochemical development and survival of the mammalian nervous system. My approach to achieve this has been one of combining all three science disciplines. My group has made major discoveries in understanding the early stages of Alzheimer’s disease, where we have pioneered new models (including the discovery that cetaceans have similar pathology) and identified potential therapeutic targets for the early stages of this disease (filed patents). Using both molecular and novel biophysical techniques, we have also discovered novel signalling pathways (including the gene Willin/FRMD6) that are involved in the growth and development of mammalian neurons, but also are involved in the pathogenesis of cancer and dementia. In addition, to overcome inherent problems with the manipulation of cells of the nervous system, in collaboration with Physicists, we helped to develop novel technology that allows the controlled poration of cell-impermeant biological material into any required cell type; the controlled growth and sorting of cells by use of light; and the development of novel imaging technologies (licensed patents). My current projects are centred on developing a new concept of how Willin/FRMD6 and the hippo signalling pathway are involved in the pathogenesis in neurodegenerative diseases, but also, we are developing novel inhibitors to a mitochondrial drug target in Alzheimer’s disease.
Tell us a fun fact about yourself:
I support Cambridge United
Why did you choose to work in dementia?
I did a Friday afternoon experiment that changed my career.
What single piece of advise would you give to an early-career researcher?
Don’t limit yourself to one discipline
What book are you reading right now? Would you recommend it?
The Lovely Bones by Alice Sebold. Yes I would recommend it, its very different.
Favourite film of all time?
Too many to choose from
Favourite ways to unplug and unwind?
Walking
What’s the best decision you ever made?
Marrying my wife Danielle
What’s your favourite vacation spot?
West Coast of Scotland
Do you collect anything?
Memories
