Not All Bad? APOE4 Sharpens Memory in Older People
APOE4, the strongest genetic risk factor for sporadic Alzheimer’s disease, & has been tied to slightly better memory in the young.
APOE4, the strongest genetic risk factor for sporadic Alzheimer’s disease, & has been tied to slightly better memory in the young.
It took more than 1m samples, but researchers have managed to extract 7 fresh Alzheimer’s loci. Published September 7 in Nature Genetics.
Staying active has many health benefits, including, perhaps, to help preserve memory. Alas, is this true in some more than others?
If clearance of amyloid would be “reasonably likely” to bestow a cognitive benefit – setting the bar rather blow there other antibodies
The FDA’s approval of aducanumab has given physicians a new treatment option, but little guidance on how to put it into practice.
Blood tests for Alzheimer’s rely on Aβ & Phosphorylated tau, they are 90% accurate, a new study suggests that a broad protein panel can do better.
Study published May 6 in Nature Neuroscience makes the case that neuronal ApoE not only signals distress, but also may have a hand in killing the neurons.
Could it be that microglia build plaques rather than bust them? Research has produced new evidence for this idea. Update from the Alz Forum
New discover around mutations in the transmembrane domain of Aβ-protein precursor cause early onset familial Alzheimer’s disease.
Could a person’s sex dictate how his or her brain reacts to amyloid? Stephen Ferguson, University of Ottawa Brain and Mind Institute, Canada, thinks it may.
Does jammed-up protein recycling in neurons cause proteins to spill into the cerebrospinal fluid in Alzheimer’s disease? Article from the Alz Forum
Once again, tau creates havoc—this time by hijacking astrocytes. According to a report in Nature from Nicolas Toni at the University of Lausanne