On their own, most genetic variations linked to Alzheimer’s disease affect a person’s risk by a minuscule amount. Together, however, they pack a wallop, This article from Alz Forum explains.
3 years ago Michal Schwartz at the Weizmann Institute of Science, deployed an immune-boosting approach pioneered for cancer in a mouse model of Alzheimer’s disease. How has this progressed?
Brush, Floss, Take a Protease Inhibitor? Do periodontal bacteria cause some cases of Alzheimer’s disease? Scientists at one start-up think so.
A comprehensive profile and comparative analysis of the characteristics, patient experience and community value of the community hospital.
A paper published online on the 21st January in Nature Medicine finds that in familial Alzheimer’s disease, blood levels of neurofilament light (NfL) rise 16 years before the predicted age…
In the January 11 Science, Yigong Shi, Tsinghua University, Beijing, and colleagues present a high-resolution cryo-electron microscopy structure of γ-secretase enfolding a fragment of APP. Find out more on their work from this post on the Alz Forum.
Researchers from University College London have strengthened the case that certain medical procedures can transfer amyloid pathology between people.
Nature Neuroscience presents a collection of Reviews on recent advances in neurodegenerative disease, highlighting shared mechanisms across diseases and the gaps in our knowledge that still need to be addressed.
Latest on investigational treatments in the pipeline. Two-part series on recent results published at the CTAD Conference from Pat McCaffrey for the Alz Forum.
Merck shook the field with news that people on verubecestat scored worse than those on placebo – find out more in this post from AlzForum
Developing computational algorithms & machine-learning techniques, to transform cross-sectional imaging data to a longitudinal picture and reconstruct the sequence of disease progression.
Many genetic variants predispose to Alzheimer’s disease, but exactly how remains a mystery.
Alz Forum
Dementia Researcher