Introducing: iPSC Collection from Tauopathy Patients
Alz ForumA multi-institutional group, including members of the Tau Consortium, unveiled a stem cell tool kit for scientists studying primary tauopathies.
Science
Genetic light bulbs illuminate the brain
Nature Careers BlogGenetically encoded voltage indicators change colour in real time when neurons transmit electrical information, offering unprecedented insight into neural activity.
MRI and Machine Learning Depict Brain Aging in Health, Disease
The human brain follows a typical ageing trajectory, but diseased brains are further along, according to a paper in the September 24 Nature Neuroscience.
Blog – My PhD plans and improving care
James WatsonJames Watson, PhD student at the University of Liverpool, explores how geography and inequality affect dementia care pathways and outcomes for older populations
Saving the Synapse: Developmental critical periods and Alzheimer’s disease – Prof Carla Shatz
Dementia ResearcherProfessor Carla Shatz’s research aims to understand how early developing brain circuits are transformed into adult connections during critical periods of development. This talk given by Professor Shatz for the UK Dementia Research Institute on the 6th September at UCL.
In Alzheimer’s, More TREM2 Is Good for You
Certain mutations in TREM2 strongly increase risk for late-onset Alzheimer’s. Could tweaking the function of this microglial receptor help people with the disease?
Blog – International collaboration: Managing primary progressive aphasia
New blog from Anna Volkmer – An international collaboration: Spreading the word on speech and language therapy approaches to managing primary progressive aphasia.
Human Microglia Make Themselves at Home in Mouse Brain
As microglia become more central to Alzheimer’s research, researchers are seeking better model systems to study their in vivo behavior – can chimeric mice provide a solution?
Physical Activity May Shield the Brain from the Onslaught of Aβ
Physical activity not only benefits the heart and the body, it may also shield the brain from the damaging effects of Aβ says study published in JAMA Neurology (July 16)
Drawing Closer: Alzheimer’s Blood Test for Primary Care
In today’s JAMA Neurology, researchers led by Oskar Hansson, Lund University, Sweden, report how a fully automated immunoassay for plasma Aβ performed when they put it through its paces.
Brain Conference Spotlights Transcriptomics, Therapeutic Strategies
Around 140 scientists gathered in Rungstedgaard, north of Copenhagen, Denmark, May 5–9 for the biannual Brain Conference organised by the Federation of European Neuroscience Societies and the Lundbeck Foundation. This article from the Alz Forum shares news from the event.
Resetting Brain Rhythms Gives Working Memory a Brief Boost
Groups of neurons fire in sync with each other across the brain when it performs a task; however, with age, they fall out of step. Can an electrical current have a restorative effect?