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MRI and Machine Learning Depict Brain Aging in Health, Disease

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The human brain follows a typical ageing trajectory, but diseased brains are further along, according to a paper in the September 24 Nature Neuroscience. Scientists led by Tobias Kaufmann and Lars Westlye, University of Oslo, Norway, analyzed structural MRI scans from 45,000 people. Most were healthy, some had a neurological disorder. The scientists found that, in general, diseased brains appear older than healthy ones, revealing a gap between their predicted and their chronological ages.

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