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Do women have a better sense of smell than men? In this Relay LIVE clip, Dr Ingrid Ekström explains what sensory health research tells us about sex differences, smell tests and ageing. Watch the full Dementia Researcher and ISTAART Relay LIVE episode: Neuroimaging and Sensory Health in Focus, hosted by Adam Smith with Dr Ingrid Ekström and Dr Sam Lockhart. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research. The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Do women have a better sense of smell than men? In this Relay LIVE clip, Dr Ingrid Ekström explains what sensory health research tells us about sex differences, smell tests and ageing.

Watch the full Dementia Researcher and ISTAART Relay LIVE episode: Neuroimaging and Sensory Health in Focus, hosted by Adam Smith with Dr Ingrid Ekström and Dr Sam Lockhart.
--

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

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We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

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YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLlRnVURDSGMxUFI4
Dementia Researcher 3.3K

Smell, Sex Differences and Dementia Risk

Dementia Researcher 08/07/2026 2:50 pm

What can the UK learn from Japan about technology and dementia care. And how might robotics, virtual reality, smart homes, and artificial intelligence support people living with dementia. This livestream is part of the Dementia Researcher weekly Showcase series. Each week we host a 45 minute online session bringing researchers together to share their work, methods, and ideas. In this session, Dr Bethany Linder @BethanyLinder shares insights from her Churchill Fellowship exploring advances in assistive dementia technology in Japan. Through visits with leading experts in robotics, virtual reality, and smart home technologies, Bethany examined how one of the world’s fastest ageing populations is using technology to support people living with dementia. The session will explore what has worked, what has not worked, and future directions in assistive technology, alongside reflections on how lessons from Japan could help improve dementia care in the UK. Bethany is a dementia researcher at the Department of Psychiatry at University of Oxford. Her work focuses on using technology to support older adults and people affected by dementia, including current research exploring how artificial intelligence could support medication management for people living with dementia. -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher Leave us a tip: https://dementia-researcher.captivate.fm/support

What can the UK learn from Japan about technology and dementia care. And how might robotics, virtual reality, smart homes, and artificial intelligence support people living with dementia.

This livestream is part of the Dementia Researcher weekly Showcase series. Each week we host a 45 minute online session bringing researchers together to share their work, methods, and ideas.

In this session, Dr Bethany Linder @BethanyLinder shares insights from her Churchill Fellowship exploring advances in assistive dementia technology in Japan. Through visits with leading experts in robotics, virtual reality, and smart home technologies, Bethany examined how one of the world’s fastest ageing populations is using technology to support people living with dementia.

The session will explore what has worked, what has not worked, and future directions in assistive technology, alongside reflections on how lessons from Japan could help improve dementia care in the UK.

Bethany is a dementia researcher at the Department of Psychiatry at University of Oxford. Her work focuses on using technology to support older adults and people affected by dementia, including current research exploring how artificial intelligence could support medication management for people living with dementia.
--

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Assistive Technology and Dementia Care

Dementia Researcher 08/07/2026 1:38 pm

Professor Frank Gunn-Moore narrates his blog written for Dementia Researcher. In this blog, Frank asks whether dementia is really unique to humans. Starting with the story of his cat Cardhu, and moving through research on dogs, dolphins, whales and other long-lived species, he explores what animal biology can teach us about memory, ageing, Alzheimer’s pathology and why some species may be more vulnerable, or more protected, than others. https://www.dementiaresearcher.nihr.ac.uk/blog-do-cats-dogs-and-dolphins-get-dementia-too/ -- Professor Frank Gunn-Moore is an academic and researcher in neurodegeneration and dementia research at the University of St Andrews, Scotland. His group has advanced understanding of the early cellular and biochemical mechanisms of Alzheimer’s disease, including links between mitochondrial and synaptic dysfunction, and has pioneered new models including the identification of Alzheimer’s-like pathology in cetaceans. His research has also identified potential therapeutic targets, novel signalling pathways such as FRMD6/Willin in the Hippo pathway, and contributed to patented optical technologies developed with industry. He has published over 150 research papers across biology, chemistry and physics, reflecting the interdisciplinary breadth of his work. Leave us a Tip https://dementia-researcher.captivate.fm/support Follow us on social media: • https://www.instagram.com/dementia_researcher/ • https://www.facebook.com/Dementia.Researcher/ • https://www.twitter.com/demrescommunity • https://www.linkedin.com/company/dementia-researcher • https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

Professor Frank Gunn-Moore narrates his blog written for Dementia Researcher.

In this blog, Frank asks whether dementia is really unique to humans. Starting with the story of his cat Cardhu, and moving through research on dogs, dolphins, whales and other long-lived species, he explores what animal biology can teach us about memory, ageing, Alzheimer’s pathology and why some species may be more vulnerable, or more protected, than others.

https://www.dementiaresearcher.nihr.ac.uk/blog-do-cats-dogs-and-dolphins-get-dementia-too/
--

Professor Frank Gunn-Moore is an academic and researcher in neurodegeneration and dementia research at the University of St Andrews, Scotland. His group has advanced understanding of the early cellular and biochemical mechanisms of Alzheimer’s disease, including links between mitochondrial and synaptic dysfunction, and has pioneered new models including the identification of Alzheimer’s-like pathology in cetaceans. His research has also identified potential therapeutic targets, novel signalling pathways such as FRMD6/Willin in the Hippo pathway, and contributed to patented optical technologies developed with industry. He has published over 150 research papers across biology, chemistry and physics, reflecting the interdisciplinary breadth of his work.

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• https://www.instagram.com/dementia_researcher/
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Professor Frank Gunn-Moore: Do Cats, Dogs and Dolphins Get Dementia Too?

Dementia Researcher 07/07/2026 10:30 pm

Frontotemporal dementia can affect far more than memory. In this clip from Relay LIVE, Dr Carmela Tartaglia explains why FTD is often linked to profound changes in behaviour, personality, empathy and relationships. As she puts it, “your brain defines you” — and when the brain changes, the person can change too. Watch the full Relay LIVE episode as Adam Smith is joined by Dr Carmela Tartaglia from the Frontotemporal Dementia PIA and Dr Michael Belloy from the Sex and Gender Differences PIA to discuss dementia research, ISTAART PIAs, sex and gender differences, FTD, biomarkers, diagnosis and AAIC. - The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research. The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Frontotemporal dementia can affect far more than memory.

In this clip from Relay LIVE, Dr Carmela Tartaglia explains why FTD is often linked to profound changes in behaviour, personality, empathy and relationships. As she puts it, “your brain defines you” — and when the brain changes, the person can change too.

Watch the full Relay LIVE episode as Adam Smith is joined by Dr Carmela Tartaglia from the Frontotemporal Dementia PIA and Dr Michael Belloy from the Sex and Gender Differences PIA to discuss dementia research, ISTAART PIAs, sex and gender differences, FTD, biomarkers, diagnosis and AAIC.
-

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

Follow us on social media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
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https://www.linkedin.com/company/dementia-researcher
https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
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We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

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YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLnR0R29hVVFPeFVj

FTD: When Brain Changes Change Personality

Dementia Researcher 06/07/2026 10:37 pm

Why should Alzheimer’s researchers study sex differences? Dr Michael Belloy explains how understanding differences between men and women could reveal new disease mechanisms, treatment pathways and opportunities for more personalised dementia care. This clip is from Relay LIVE, part of the Dementia Researcher x ISTAART Relay podcast series, recorded ahead of AAIC. Watch the full episode to hear more from Dr Michael Belloy and Dr Carmela Tartaglia on sex, gender and frontotemporal dementia research. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

Why should Alzheimer’s researchers study sex differences?

Dr Michael Belloy explains how understanding differences between men and women could reveal new disease mechanisms, treatment pathways and opportunities for more personalised dementia care.

This clip is from Relay LIVE, part of the Dementia Researcher x ISTAART Relay podcast series, recorded ahead of AAIC.

Watch the full episode to hear more from Dr Michael Belloy and Dr Carmela Tartaglia on sex, gender and frontotemporal dementia research.
--

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

Follow us on social media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://www.twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

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YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLjdlX2hpMWpveTlR

Why Sex Differences in Alzheimer’s Matter

Dementia Researcher 06/07/2026 10:14 pm

Clinical trials are not only important for testing treatments — they can also teach researchers how to build stronger studies. In this clip from the @alzassociation ISTAART Relay podcast, Dr Carla Abdelnour explains why understanding clinical trial design can help researchers think more clearly about protocols, outcomes, inclusion and exclusion criteria, and sample size. Watch or listen to the full episode as Dr Sindhuja Govindarajan from the PEERs PIA speaks with Carla Abdelnour from the Clinical Trials Advancement and Methods PIA about biomarkers, mixed pathologies, trial methods, global representation and how early career researchers can get involved with ISTAART. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

Clinical trials are not only important for testing treatments — they can also teach researchers how to build stronger studies.

In this clip from the @alzassociation ISTAART Relay podcast, Dr Carla Abdelnour explains why understanding clinical trial design can help researchers think more clearly about protocols, outcomes, inclusion and exclusion criteria, and sample size.

Watch or listen to the full episode as Dr Sindhuja Govindarajan from the PEERs PIA speaks with Carla Abdelnour from the Clinical Trials Advancement and Methods PIA about biomarkers, mixed pathologies, trial methods, global representation and how early career researchers can get involved with ISTAART.
--

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

Follow us on social media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://www.twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

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Clinical Trials: A Gold Standard for Research

Dementia Researcher 06/07/2026 9:42 pm

Dr Sam Moxon narrates his blog written for Dementia Researcher. You develop something genuinely different, cost it, build the team, submit it feeling confident, and then the rejection lands. In this blog, Dr Sam Moxon sits with the researchers who keep watching their most original ideas fall at the panel while safer, more familiar work sails through. He asks a question the field tends to avoid: are our funders too risk averse to back the ideas that might actually change things, and what does that caution do to the people early in their careers who cannot afford to fail? https://www.dementiaresearcher.nihr.ac.uk/blog-why-some-ideas-never-get-a-chance/ -- Dr Sam Moxon is a biomaterials Research Fellow at University of Birmingham. His expertise falls on the interface between biology and engineering. His PhD focussed on regenerative medicine and he now works on trying to develop 3D bioprinting techniques with human stem cells, so that we better understand and treat degenerative diseases. He is also the Founder and CEO of Aegis FibreTech. Outside of the lab he hikes through the Lake District and is an expert on all things Disney. -- Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support. -- Leave us a Tip https://dementia-researcher.captivate.fm/support Follow us on social media: • https://www.instagram.com/dementia_researcher/ • https://www.facebook.com/Dementia.Researcher/ • https://www.twitter.com/demrescommunity • https://www.linkedin.com/company/dementia-researcher • https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

Dr Sam Moxon narrates his blog written for Dementia Researcher.

You develop something genuinely different, cost it, build the team, submit it feeling confident, and then the rejection lands. In this blog, Dr Sam Moxon sits with the researchers who keep watching their most original ideas fall at the panel while safer, more familiar work sails through. He asks a question the field tends to avoid: are our funders too risk averse to back the ideas that might actually change things, and what does that caution do to the people early in their careers who cannot afford to fail?

https://www.dementiaresearcher.nihr.ac.uk/blog-why-some-ideas-never-get-a-chance/
--

Dr Sam Moxon is a biomaterials Research Fellow at University of Birmingham. His expertise falls on the interface between biology and engineering. His PhD focussed on regenerative medicine and he now works on trying to develop 3D bioprinting techniques with human stem cells, so that we better understand and treat degenerative diseases. He is also the Founder and CEO of Aegis FibreTech. Outside of the lab he hikes through the Lake District and is an expert on all things Disney.
--

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you by University College London in association with the National Institute for Health and Care Research, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.
--

Leave us a Tip
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• https://www.instagram.com/dementia_researcher/
• https://www.facebook.com/Dementia.Researcher/
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• https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
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YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLlpGRXU2Q1FFb244

Dr Sam Moxon - Why Some Ideas Never Get a Chance

Dementia Researcher 06/07/2026 2:38 pm

Welcome to the seventh season of the Dementia Researcher X ISTAART PIA Relay Podcast. Across six episodes, leading early career and senior researchers hand the mic from one ISTAART PIA to the next, giving you an honest, peer-to-peer tour of where dementia research is actually heading, from wearables and biomarkers to policy and trial design, in the run-up to AAIC. Series closer, and the relay comes full circle: Dr Carla Abdelnour, who hosted episode one, returns as the guest. Carla is a clinician scientist in Barcelona and incoming Chair of the ISTAART Clinical Trials Advancement and Methods PIA, working on mixed neurodegenerative disease, particularly Lewy body and Alzheimer's pathology together. With host Dr Sindhuja Tirumalai Govindarajan she explains why co-pathology is so common and what it means for treatment: does someone with both alpha-synuclein and Alzheimer's pathology respond to an anti-amyloid drug the same way as someone without? They discuss why she leans on fluid biomarkers, the wish for a synuclein PET tracer, and how trials might stratify or include people by co-pathology. Carla makes a useful point for anyone designing research, that clinical trial methods translate straight to observational studies, and previews the CTAM PIA's AAIC programme, including a panel and featured session on global representation in trials. Takeaways • Mixed pathology is common, and co-occurring alpha-synuclein and Alzheimer's pathology may change how people respond to treatment. • Trials could stratify or include people by co-pathology, but alpha-synuclein is currently detectable only in CSF, which limits that. • Fluid biomarkers offer the specificity to track different proteinopathies and, potentially, response to treatment. • Clinical trial design transfers straight to observational research: the same inclusion criteria, outcomes and sample-size thinking. • Global representation in trials is a live priority, with a CTAM panel launching at AAIC. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research. The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors. Chapters 00:00 Introduction to the series 01:14 Dr Carla Abdelnour’s research background 03:54 Mixed pathology in dementia 07:18 Biomarkers and imaging methods 10:08 Bringing biomarkers into trials 13:40 Inside the CTAM PIA 20:47 AAIC sessions and member involvement 24:59 Clinical trials vs. research studies 28:04 Promising trials in Lewy body disease 29:10 Advice for new members 31:26 Final thoughts on collaboration

Welcome to the seventh season of the Dementia Researcher X ISTAART PIA Relay Podcast. Across six episodes, leading early career and senior researchers hand the mic from one ISTAART PIA to the next, giving you an honest, peer-to-peer tour of where dementia research is actually heading, from wearables and biomarkers to policy and trial design, in the run-up to AAIC.

Series closer, and the relay comes full circle: Dr Carla Abdelnour, who hosted episode one, returns as the guest. Carla is a clinician scientist in Barcelona and incoming Chair of the ISTAART Clinical Trials Advancement and Methods PIA, working on mixed neurodegenerative disease, particularly Lewy body and Alzheimer's pathology together. With host Dr Sindhuja Tirumalai Govindarajan she explains why co-pathology is so common and what it means for treatment: does someone with both alpha-synuclein and Alzheimer's pathology respond to an anti-amyloid drug the same way as someone without? They discuss why she leans on fluid biomarkers, the wish for a synuclein PET tracer, and how trials might stratify or include people by co-pathology. Carla makes a useful point for anyone designing research, that clinical trial methods translate straight to observational studies, and previews the CTAM PIA's AAIC programme, including a panel and featured session on global representation in trials.

Takeaways

• Mixed pathology is common, and co-occurring alpha-synuclein and Alzheimer's pathology may change how people respond to treatment.
• Trials could stratify or include people by co-pathology, but alpha-synuclein is currently detectable only in CSF, which limits that.
• Fluid biomarkers offer the specificity to track different proteinopathies and, potentially, response to treatment.
• Clinical trial design transfers straight to observational research: the same inclusion criteria, outcomes and sample-size thinking.
• Global representation in trials is a live priority, with a CTAM panel launching at AAIC.
--

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

Follow us on social media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://www.twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Chapters

00:00 Introduction to the series
01:14 Dr Carla Abdelnour’s research background
03:54 Mixed pathology in dementia
07:18 Biomarkers and imaging methods
10:08 Bringing biomarkers into trials
13:40 Inside the CTAM PIA
20:47 AAIC sessions and member involvement
24:59 Clinical trials vs. research studies
28:04 Promising trials in Lewy body disease
29:10 Advice for new members
31:26 Final thoughts on collaboration

1 0

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLjB4N2h6bF9OZktV

ISTAART Relay Podcast - Clinical Trials Advancement and Methods PIA 2026

Dementia Researcher 04/07/2026 8:00 am

How can early career dementia researchers access mentoring, training and global opportunities? In this clip from the #istaart Relay Podcast, Sindhuja Tirumalai Govindarajan explains how the PEERs PIA supports early career researchers across dementia research, from professional development and advocacy to virtual programming and local networking. Watch the full episode to hear more about PEERs, neuroimaging, machine learning, #AAIC26, and building a more connected research community. #dementiaresearch #dementia -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research. The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

How can early career dementia researchers access mentoring, training and global opportunities?

In this clip from the #istaart Relay Podcast, Sindhuja Tirumalai Govindarajan explains how the PEERs PIA supports early career researchers across dementia research, from professional development and advocacy to virtual programming and local networking.

Watch the full episode to hear more about PEERs, neuroimaging, machine learning, #AAIC26, and building a more connected research community. #dementiaresearch #dementia
--

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

Follow us on social media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://www.twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

0 0

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLk1QTDlRZVVPTzc0

How PEERs Supports Early Career Dementia Researchers

Dementia Researcher 03/07/2026 1:46 pm

Welcome to the seventh season of the Dementia Researcher X ISTAART PIA Relay Podcast. Across six episodes, leading early career and senior researchers hand the mic from one ISTAART PIA to the next, giving you an honest, peer-to-peer tour of where dementia research is actually heading, from wearables and biomarkers to policy and trial design, in the run-up to AAIC. Most people with hypertension after 50 never develop dementia, so what separates those who do? That is the question driving Sindhuja Tirumalai Govindarajan, a neuroimaging researcher and outgoing Chair of the ISTAART PEERs PIA, recorded as she moves from a postdoc at the University of Pennsylvania to an assistant professorship at the Karolinska Institute. With host Joe Kane she explains how machine learning on tens of thousands of MRI scans can pick up subtle brain changes years before symptoms, and why scans from different scanners have to be harmonised first. The conversation then turns to PEERs itself, a PIA built not around one research area but around early career researchers everywhere, and the work of levelling opportunity across borders through local routes like Neuroscience Next, WYLD and INTERDEM Academy. Sindhuja runs through the PIA's AAIC workshops, from narrative CVs to social bingo for ECRs, and closes with practical advice on getting people involved: make the ask specific. Takeaways • Machine learning on large MRI datasets can detect brain changes years before any cognitive symptoms show. • Scans from different scanners must be harmonised first, stripping out machine noise so only the biology remains. • PEERs exists to level opportunity for early career researchers wherever they are, across every research area. • Local routes such as Neuroscience Next, WYLD and INTERDEM Academy widen access for those who cannot get to the big conference. • Interest among ECRs is common but clarity often is not, so make the ask specific and people will step up. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between. Find out more at https://istaart.alz.org/ -- A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk. Leave us a tip: https://dementia-researcher.captivate.fm/support Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Download and Register with our Community App: https://www.onelink.to/dementiaresearcher We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research. The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors. Chapters 00:00 Introduction to the Podcast and Guests 01:58 Sindhuja's Research Journey and Neuroimaging in Dementia 07:31 Exciting Developments in Dementia Research 11:03 Challenges and Opportunities for Early Career Researchers 15:39 The Role of PIA in Supporting Researchers 20:41 Sindhuja's Personal Journey in the PIA 25:10 Engagement Strategies for Early Career Researchers 29:05 Conclusion and Future Directions

Welcome to the seventh season of the Dementia Researcher X ISTAART PIA Relay Podcast. Across six episodes, leading early career and senior researchers hand the mic from one ISTAART PIA to the next, giving you an honest, peer-to-peer tour of where dementia research is actually heading, from wearables and biomarkers to policy and trial design, in the run-up to AAIC.

Most people with hypertension after 50 never develop dementia, so what separates those who do? That is the question driving Sindhuja Tirumalai Govindarajan, a neuroimaging researcher and outgoing Chair of the ISTAART PEERs PIA, recorded as she moves from a postdoc at the University of Pennsylvania to an assistant professorship at the Karolinska Institute. With host Joe Kane she explains how machine learning on tens of thousands of MRI scans can pick up subtle brain changes years before symptoms, and why scans from different scanners have to be harmonised first. The conversation then turns to PEERs itself, a PIA built not around one research area but around early career researchers everywhere, and the work of levelling opportunity across borders through local routes like Neuroscience Next, WYLD and INTERDEM Academy. Sindhuja runs through the PIA's AAIC workshops, from narrative CVs to social bingo for ECRs, and closes with practical advice on getting people involved: make the ask specific.

Takeaways

• Machine learning on large MRI datasets can detect brain changes years before any cognitive symptoms show.
• Scans from different scanners must be harmonised first, stripping out machine noise so only the biology remains.
• PEERs exists to level opportunity for early career researchers wherever they are, across every research area.
• Local routes such as Neuroscience Next, WYLD and INTERDEM Academy widen access for those who cannot get to the big conference.
• Interest among ECRs is common but clarity often is not, so make the ask specific and people will step up.
--

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.
There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/
--

A transcript of this show, links and show notes and profiles on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

Leave us a tip:
https://dementia-researcher.captivate.fm/support

Follow us on social media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://www.twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
https://bsky.app/profile/dementiaresearcher.bsky.social

Download and Register with our Community App:
https://www.onelink.to/dementiaresearcher

We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Chapters

00:00 Introduction to the Podcast and Guests
01:58 Sindhuja's Research Journey and Neuroimaging in Dementia
07:31 Exciting Developments in Dementia Research
11:03 Challenges and Opportunities for Early Career Researchers
15:39 The Role of PIA in Supporting Researchers
20:41 Sindhuja's Personal Journey in the PIA
25:10 Engagement Strategies for Early Career Researchers
29:05 Conclusion and Future Directions

0 0

YouTube Video VVVlMXF2MEUxVXpOUHRHaHoyblFhb2lnLllYSktjekNRbmx3

ISTAART Relay Podcast - PIA for Early Career Researchers (PEERS) 2026

Dementia Researcher 03/07/2026 8:00 am

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