Profile – Makis Tzioras

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Makis Tzioras

Job Title:

PhD student

Place of work / study:

The University of Edinburgh, UK Dementia Research Institute

Area of research:

Alzheimer’s disease / Microglia and Synapse Loss

How is your work currently funded:

UK Dementia Research Institute, Alzheimer’s Research UK

Tell us a little about yourself:            

I originally come from Athens, Greece but moved to Edinburgh when I was 17 to study Biomedical Sciences. Since then, Scotland has become a second home and I feel very grateful to be doing my PhD with a wonderful supervisor, Tara Spires-Jones. In my PhD, I am very lucky to be working with human post-mortem tissue where I am investigating how microglial cells go awry and study their contribution to synapse loss in Alzheimer’s disease.

Tell us a fun fact about yourself:

I think I subconsciously ended-up working on microglia eating synapses to satisfy an ancestral trait of eating culture due to my Greek-Jewish background. Also, my drag alter-ego is Princess Glea.

Why did you choose to work in dementia?

During my undergraduate degree, I was fascinated by the concept of memory, and how it’s a common process in everyone, yet so different between people. From a scientific perspective, I was then curious to understand how memory is lost in dementia which led me to work on Alzheimer’s disease, the most common form of dementia. Since then, I took a particular interest in how the immune system is involved in maintaining brain health but can also contribute to disease pathogenesis.

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