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TORONTO, July 30, 2025 — Taking a combination of common drugs used to treat blood pressure, cholesterol and diabetes may have an added benefit: slower cognitive decline. A study of more than 4,500 older adults showed cognitive test scores similar to people three years younger for participants who took a combination of drugs targeting vascular or metabolic conditions, all of which are known risk factors for dementia.
Participants who were on all three of the vascular drugs had the greatest cognitive benefits, and their brains showed fewer signs of Alzheimer’s-related changes at autopsy. For those who took only two of the drugs, the most effective pairing for cognitive protection was blood pressure and cholesterol drugs.
About the Alzheimer’s Association International Conference® (AAIC®)
The Alzheimer’s Association International Conference (AAIC) is the world’s largest gathering of researchers from around the world focused on Alzheimer’s and other dementias. As a part of the Alzheimer’s Association’s research program, AAIC serves as a catalyst for generating new knowledge about dementia and fostering a vital, collegial research community.
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About the Alzheimer’s Association®
The Alzheimer’s Association is a worldwide voluntary health organization dedicated to Alzheimer’s care, support and research. Our mission is to lead the way to end Alzheimer’s and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. Our vision is a world without Alzheimer’s and all other dementia®. Visit alz.org or call +1 800.272.3900.
Dementia Researcher
