TORONTO, July 27, 2025 — New research announced at AAIC 2025 sheds light on crucial differences between men and women in risk for Alzheimer’s and other diseases that cause dementia. One study found that traumatic brain injuries (TBIs, a well-known risk factor for dementia) were more likely to shrink dementia-related areas of the brain in women than men. Another looked closer at “chemobrain” — declines in thinking and memory reported by about one-third of women receiving breast cancer chemotherapy.
Women make up nearly two-thirds of the more than 7 million Americans living with Alzheimer’s. The chemobrain study is the first to show that brain changes, inflammation and shrinkage related to the cancer treatment are connected to symptoms like memory lapses and trouble focusing or finding words. The study adds to growing evidence that chemotherapy impacts brain health.
The Alzheimer’s Association supports research to better understand sex-based differences in cognitive health and prevent negative side effects for chemo patients. Clinicians can learn more about early detection, diagnosis and treatment of dementia using ALZPro, the newly-launched library of online tools and resources for professionals from the Alzheimer’s Association.
About the Alzheimer’s Association International Conference® (AAIC®)
The Alzheimer’s Association International Conference (AAIC) is the world’s largest gathering of researchers from around the world focused on Alzheimer’s and other dementias. As a part of the Alzheimer’s Association’s research program, AAIC serves as a catalyst for generating new knowledge about dementia and fostering a vital, collegial research community.
Alzheimer’s Association: alz.org
AAIC: alz.org/aaic
AAIC newsroom: alz.org/AAICpress
AAIC 2025 hashtag: #AAIC25
About the Alzheimer’s Association®
The Alzheimer’s Association is a worldwide voluntary health organization dedicated to Alzheimer’s care, support and research. Our mission is to lead the way to end Alzheimer’s and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. Our vision is a world without Alzheimer’s and all other dementia®. Visit alz.org or call +1 800.272.3900.

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