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AAIC Neuroscience Next Manchester brought together over 200 early career researchers from across the biomarker field, and we were proud to recognise a group of outstanding local award winners whose work stood out for its quality, clarity and impact.
Poster Winner
Mohammad Nasser, University of Sussex
Frontotemporal Dementia Causing P301S Mutation Alters Non-phosphorylated Tau Redistribution In The Nucleolus In SH-SY5Y Cells
Mohammad’s poster explored how the P301S mutation linked to frontotemporal dementia influences the intracellular redistribution of non phosphorylated tau, with a particular focus on nucleolar changes in SH SY5Y cells. The work offered a careful cellular perspective on tau biology and generated strong interest during the poster discussions.
Lightning Talk Runner Up
Luna Nordenström, University College London
Online Keyboard Tapping As A Digital Biomarker For Early Frontotemporal Dementia
Luna presented an accessible and engaging talk on the use of online keyboard tapping metrics as a potential early digital biomarker for frontotemporal dementia. The approach highlights how simple, scalable digital measures could contribute to earlier detection.
Lightning Talk Winner
Lorenzo Barcellos, Universidade Federal do Rio Grande do Sul, Brazil
Brain Atrophy Patterns Associate With Biological Staging Defined By PET In Preclinical Alzheimer’s Disease
Lorenzo’s winning presentation examined how structural brain atrophy patterns align with PET defined biological staging in preclinical Alzheimer’s disease. The work brought imaging and biomarker frameworks together in a clear and clinically relevant way.
Showstopper Runner Up
Ellie Crispin, University College London
Measuring Nptx1 In Extracellular Vesicles From Genetic Frontotemporal Dementia Mutation Carriers
Ellie’s talk focused on measuring Nptx1 in extracellular vesicles from individuals carrying genetic frontotemporal dementia mutations. The study highlighted the potential of vesicle based biomarkers to improve our understanding of early pathological change.
Showstopper Winner
Dr Andreia Rocha, University of Pittsburgh
Tracking tau spread: MK6240 assigns higher Braak stages than Flortaucipir
Andreia’s award winning presentation compared tau PET tracers, showing that MK6240 assigns higher Braak stages than Flortaucipir. The findings prompted lively discussion around staging, tracer selection and implications for clinical trials.
These awards reflect the depth and diversity of talent within the early career community. Each of these researchers delivered work of a very high standard and contributed to a strong, focused programme centred on biomarker advancements in dementia diagnosis.
Congratulations to all our winners and runners up. It was a pleasure to showcase your research in Manchester.
