Dr Tom Phillips, Research Associate for the UK Dementia Research Institute at Cardiff University, talks about microglia’s role in dementia (mostly Alzheimer’s Disease but also Parkinson’s Disease), how that role moves between protective (clearance) and damaging (neuroinflammation) and how new genetic findings point to new therapies. The fill title for this talk is “Microglia a double edged sword: Neuroinflammation and new routes for drug discovery”.
Microglia are increasingly recognised as key component in a variety of neurodegenerative conditions including Alzheimer’s and Parkinson’s disease. While microglia have a protective role in these conditions the dysfunction of these cells can lead to neuroinflammation and is believed to be linked to disease progression. Recently risk genes found in microglia have opened a new therapeutic pathway.
This Midday Lecture Webinar was recorded on the 20th May 2020 and is brought to you by the NIHR Dementia Researcher Website, and hosted by Adam Smith, Programme Director at the Office of the NIHR National Director for Dementia Research, University College London
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