Physical Activity May Shield the Brain from the Onslaught of Aβ

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Physical activity not only benefits the heart and the body, it may also shield the brain from the damaging effects of Aβ. That’s according to findings presented at the Alzheimer’s Association International Conference, held July 14–18 in Los Angeles. Active people in their 70s were less likely to suffer the cognitive and neurodegenerative consequences of Aβ deposition than their more sedentary peers, said Jennifer Rabin, Massachusetts General Hospital in Charlestown. Good vascular health also held Aβ-related damage in check, although it appeared to do so independently of physical activity, she said. The study, led by Jasmeer Chhatwal at MGH, was published July 16 in JAMA Neurology.

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