Forced Into Fat-Burning Mode, Microglia Gobble Up Plaques
Scientists led by Jie Zhang, Xiamen University, reported that hexokinase 2—a pivotal enzyme in glucose metabolism—ramps up in microglia in the AD brain.
Scientists led by Jie Zhang, Xiamen University, reported that hexokinase 2—a pivotal enzyme in glucose metabolism—ramps up in microglia in the AD brain.
The Lancet Neurology 20th Anniversary Lecture: “The relevance of social and commercial determinants for neurological health”.
Eisai confirms phase 3 Amyloid drug trial success with Clarity AD and sets sights on US, Euope and Japan approvals by March 2023
New blog from Dr Yvonne Couch providing a history of angiogenesis, and how after brain injury and in old age this may contribute to brain health.
Results from the I-CONECT project, led by Hiroko Dodge of Oregon Health and Science University in Portland, sharing benefits of social contact
Persistent loss of smell may be a better predictor of long-term cognitive and functional impairment than severity of the initial COVID-19 infection
Are we ready for blood based biomarkers? New publication shared at the AAIC explores the benefits and risks of their use in clinical practice and research
In this blog Dr Kamar Ameen-Ali explores alternatives to mammalian models and considers whether they can drive a breakthrough
Mouse models of amyloidosis, poorly acidified lysosomes stuffed with Aβ distort the plasma membranes of neurons and form toxic rosettes around their nuclei.
MND Research Leaders – Prof Justin Yerbury, Prof Lezanne Ooi & Dr Luke McAlary discuss their research from protein misfolding to drug discovery
Could the bias towards studying male animals account for poor translation of preclinical dementia research to clinical? Dr Kamar Ameen-Ali explores
Sleep is increasingly recognised as important in dementia but do Cannabinoids help? Masha Burelo, PhD Student from University of Aberdeen explores
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