Lecanemab Phase 3 Trial Meetings Primary Endpoint
Dementia ResearcherEisai confirms phase 3 Amyloid drug trial success with Clarity AD and sets sights on US, Euope and Japan approvals by March 2023
Science
Blog – Angiogenesis
Dr Yvonne CouchNew blog from Dr Yvonne Couch providing a history of angiogenesis, and how after brain injury and in old age this may contribute to brain health.
A Chat Every Other Day Keeps Dementia at Bay?
Alz ForumResults from the I-CONECT project, led by Hiroko Dodge of Oregon Health and Science University in Portland, sharing benefits of social contact
Persistent Loss of Smell Due to COVID-19 Closely Connected to Long-Lasting Cognitive Problems
Alzheimer's AssociationPersistent loss of smell may be a better predictor of long-term cognitive and functional impairment than severity of the initial COVID-19 infection
Recommendations for use of Alzheimer’s “Blood Tests”
Are we ready for blood based biomarkers? New publication shared at the AAIC explores the benefits and risks of their use in clinical practice and research
Blog – Is it time to look at alternatives to rodent models?
Dr Kamar Ameen-AliIn this blog Dr Kamar Ameen-Ali explores alternatives to mammalian models and considers whether they can drive a breakthrough
Behold PANTHOS, a Toxic Wreath of Perinuclear Aβ That Kills Neurons
Mouse models of amyloidosis, poorly acidified lysosomes stuffed with Aβ distort the plasma membranes of neurons and form toxic rosettes around their nuclei.
MND Research – The Future
MND Research Leaders – Prof Justin Yerbury, Prof Lezanne Ooi & Dr Luke McAlary discuss their research from protein misfolding to drug discovery
Blog – The importance of including both sexes in preclinical dementia research
Could the bias towards studying male animals account for poor translation of preclinical dementia research to clinical? Dr Kamar Ameen-Ali explores
Blog – Cannabinoids for better sleep?
Masha BureloSleep is increasingly recognised as important in dementia but do Cannabinoids help? Masha Burelo, PhD Student from University of Aberdeen explores
Study reveals new genes associated with Alzheimer’s
UK DRIUK DRI study identifies 75 genes associated with an increased risk of developing Alzheimer’s disease, including 42 new genes not previously implicated
Blog – Pesticides in Cannabis
Masha Burelo from University of Aberdeen has an interest in Cannabis an Cannabinoids in her latest blog in this series she discusses some of the risks