Research News

Lifestyle Change Benefits May Be Strongest for Carriers of Alzheimer’s Risk Gene

News from AAIC 2025

Reading Time: 2 minutes

Lifestyle Change Benefits May Be Strongest for Carriers of Alzheimers Risk GeneTORONTO, July 31, 2025 — People with a higher genetic risk for Alzheimer’s disease may benefit the most from healthy lifestyle interventions like walking, according to a decade of data from three large international studies. Older adults who carry the Alzheimer’s risk gene known as APOE4 had higher cognitive benefits from non-drug interventions like exercise, diet and cognitive training than non-carriers.

In this study, walking was found to be the most effective healthy habit for slowing down cognitive damage. Like many healthy lifestyle changes, the key was making it a habit, as the study showed that sticking with it for at least two years produced cognitive benefits up to seven years later.


About the Alzheimer’s Association International Conference® (AAIC®)
The Alzheimer’s Association International Conference (AAIC) is the world’s largest gathering of researchers from around the world focused on Alzheimer’s and other dementias. As a part of the Alzheimer’s Association’s research program, AAIC serves as a catalyst for generating new knowledge about dementia and fostering a vital, collegial research community.
Alzheimer’s Association: alz.org
AAIC: alz.org/aaic
AAIC newsroom: alz.org/AAICpress
AAIC 2025 hashtag: #AAIC25


About the Alzheimer’s Association®
The Alzheimer’s Association is a worldwide voluntary health organization dedicated to Alzheimer’s care, support and research. Our mission is to lead the way to end Alzheimer’s and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. Our vision is a world without Alzheimer’s and all other dementia®. Visit alz.org or call +1 800.272.3900.

Comments 1

  1. Mark James

    Very interesting research on how lifestyle changes may help reduce cognitive decline, especially for people with higher genetic risk of Alzheimer’s. Small daily habits can have a long-term impact on overall health.

Leave a comment

Your email address will not be published. Required fields are marked *

Alzheimer's Association

The Alzheimer's Association leads the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support.

Having trouble receiving our newsletter?

Earlier this week, we discovered that Microsoft email services appear to be blocking or delaying delivery of our newsletter.

We are working to resolve as soon as possible. However, if you use Hotmail, MSN Hotmail, MSN Mail, Windows Live Mail or Outlook.com, you may have missed last week’s newsletter and could continue to experience delivery issues until the problem is fixed.

In the meantime, you can subscribe again using an alternative email address via the link below. Once delivery returns to normal, you can remove one of your subscriptions if you start receiving duplicates.

No Thanks

Translate »